MSM

Helps form bridges that shape and stabilize some protein structures. Needed for healthy hair, skin, and nails.

Best MSM

Sale#1 Real Supplements Rated Best in 2020
Doctor's Best MSM Powder with OptiMSM, Non-GMO, Vegan, Gluten Free, Soy Free, 250 Grams
10,187 Reviews
Doctor's Best MSM Powder with OptiMSM, Non-GMO, Vegan, Gluten Free, Soy Free, 250 Grams
  • DOCTOR’S BEST MSM FEATURES OPTIMSM - with OptiMSM a high quality purified MSM (methylsulfonylmethane) backed by numerous clinical studies for safety and efficacy.MSM is a natural sulfur compound that helps support the formation of healthy connective tissues. It also helps support overall joint mobility, and a normal range of motion. It also may help reduce oxidative damage to support a immune system
  • BENEFITS TO JOINTS: MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. Improves joint function and helps protect cartilage, mobility, reduces joint pain, increases range of motion.*
  • IMMUNE SUPPORT: MSM provides support for immune function, and for the body’s antioxidant and overall protective capacities resulting in a stronger immune response.*
  • NATURE’S BEAUTY MINERAL: MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails.*
  • CLINICAL STUDIES: Sulfur continues to be an important dietary nutrient to support healthy aging. With its regulation of glutathione and other ways in the body, MSM can help support healthy skin, joint mobility, cartilage, and the antioxidant response.
#2 Real Supplements Rated Best in 2020
Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 360 Capsules
2,931 Reviews
Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 360 Capsules
  • DOCTOR’S BEST MSM FEATURES OPTIMSM: with OptiMSM a high quality purified MSM (methylsulfonylmethane) backed by numerous clinical studies for safety and efficacy.MSM is a natural sulfur compound that helps support the formation of healthy connective tissues.
  • BENEFITS TO JOINTS: MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. Improves joint function and helps protect cartilage, mobility, reduces joint pain, increases range of motion.
  • IMMUNE SUPPORT: MSM provides support for immune function, and for the body’s antioxidant and overall protective capacities resulting in a stronger immune response.
  • NATURE’S BEAUTY MINERAL: MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails.
  • NATURE’S BEAUTY MINERAL: MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails.
Sale#3 Real Supplements Rated Best in 2020
NOW Supplements, MSM (Methylsulfonylmethane) 1,000 mg, Joint Health*, 120 Veg Capsules
621 Reviews
NOW Supplements, MSM (Methylsulfonylmethane) 1,000 mg, Joint Health*, 120 Veg Capsules
  • JOINT SULFUR FOR CONNECTIVE TISSUE*: MSM, in its role in the body's sulfur cycle, helps to create the chemical links needed to form and maintain numerous different types of structural tissues of the human body, including connective tissues, such as articular cartilage and skin.*
  • VEGAN CAPSULES/SUPPORTS HEALTHY CARTILAGE*: Sulfur compounds are found in all body cells and are indispensable for life.*
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Dairy Free, Egg Free, Made without Gluten, Corn Free, Soy Free, Kosher, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968
Sale#4 Real Supplements Rated Best in 2020
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1500 mg, 120 Tablets (DRB-00097)
3,055 Reviews
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1500 mg, 120 Tablets (DRB-00097)
  • DOCTOR’S BEST MSM FEATURES OPTIMSM - with OptiMSM a high quality purified MSM (methylsulfonylmethane) backed by numerous clinical studies for safety and efficacy.MSM is a natural sulfur compound that helps support the formation of healthy connective tissues. It also helps support overall joint mobility, and a normal range of motion. It also may help reduce oxidative damage to support a immune system
  • BENEFITS TO JOINTS – MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. Improves joint function and helps protect cartilage, mobility, reduces joint pain, increases range of motion
  • IMMUNE SUPPORT - MSM provides support for immune function, and for the body’s antioxidant and overall protective capacities resulting in a stronger immune response
  • NATURE’S BEAUTY MINERAL - MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails
  • CLINICAL STUDIES - Sulfur continues to be an important dietary nutrient to support healthy aging. With its regulation of glutathione and other ways in the body, MSM can help support healthy skin, joint mobility, cartilage, and the antioxidant response.
Sale#5 Real Supplements Rated Best in 2020
NOW Supplements, MSM (Methylsulfonylmethane) 1,000 mg, Joint Health*, 240 Veg Capsules
2,911 Reviews
NOW Supplements, MSM (Methylsulfonylmethane) 1,000 mg, Joint Health*, 240 Veg Capsules
  • JOINT SULFUR FOR CONNECTIVE TISSUE*: MSM, in its role in the body's sulfur cycle, helps to create the chemical links needed to form and maintain numerous different types of structural tissues of the human body, including connective tissues, such as articular cartilage and skin.*
  • VEGAN CAPSULES/SUPPORTS HEALTHY CARTILAGE*: Sulfur compounds are found in all body cells and are indispensable for life.*
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Dairy Free, Egg Free, Made without Gluten, Corn Free, Soy Free, Kosher, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968
#6 Real Supplements Rated Best in 2020
Pure Encapsulations MSM Capsules | Sulfur Supplement to Support Joints, Immune System, Connective Tissue, and Respiratory Health* | 250 Capsules
366 Reviews
Pure Encapsulations MSM Capsules | Sulfur Supplement to Support Joints, Immune System, Connective Tissue, and Respiratory Health* | 250 Capsules
  • Joint Health: MSM is a naturally-derived sulfur formula that helps support joint functionality and comfort, specifically connective tissue health.*
  • Immune Function: Methylsulfonylmethane (or dimethylsulfone) provides potential support for healthy immune function.*
  • Hair, Skin, & Nails: Sulfur also supports tissue containing significant amounts of collagen and keratin, including hair, skin, and nails.*
  • Pure Quality: Our supplements are made with only premium ingredients sourced from trusted suppliers and guided by our nutritional experts, then carefully manufactured and tested to verify their potency and purity.
  • Pure Difference: What makes us different isn't just our process or what goes into our supplements -- what we leave out matters, too. Pure Encapsulations products are FREE FROM wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.
Sale#7 Real Supplements Rated Best in 2020
Doctor's Best Glucosamine Chondroitin Msm with OptiMSM Capsules, Supports Healthy Joint Structure, Function & Comfort, Non-GMO, Gluten Free, Soy Free, 240 Count (Pack of 1)
  • Glucosamine/chondroitin/MSM with optimism: the ultimate combination for healthy joints! Glucosamine supplements are used to help prevent the breakdown of joint tissues and any associated symptoms including pain, lack of flexion, joint stiffness and weakness. Chondroitin helps keep joints healthy by absorbing fluid (particularly water) in the bones. Msm provides a source of dietary sulfur and half of the body’s sulfur is found in the skin, muscles, and bones. Sulfur is a critical building blocker, strengthens joint tissues and helps with elasticity.*
  • Improve joint flexibility: a potent combination of three proven, purified ingredients that help build and serves as a shock absorber for your joints. Healthy joints may get worn away by sports injuries, overuse, or wear-and-tear that can cause joint discomfort.*
  • Benefits of glucosamine/chondroitin/MSM with optimism: helps supports joint mobility, joint structure, and can increase joint flexibility while protecting joint tissue. Also supports overall health for hair, skin, and nails.*
  • Clinically-studied optimism: Glucosamine/chondroitin/MSM with optimism clinically proven, purified ingredients to improve joint function and mobility, combined into one supplement. Provides you with the perfect combination of potent dietary supplements that will help you maintain and support your joint healthy throughout your active Lifetime.*
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Sale#8 Real Supplements Rated Best in 2020
Jarrow Formulas MSM 1000 mg - 200 Veggie Caps - Methylsulfonylmethane - Important Source of Organic Sulfur - Strengthens Joints - Up to 200 Servings
1,724 Reviews
Jarrow Formulas MSM 1000 mg - 200 Veggie Caps - Methylsulfonylmethane - Important Source of Organic Sulfur - Strengthens Joints - Up to 200 Servings
  • Important Source of Organic Sulfur: Jarrow Formulas MSM is an organic source of bioavailable sulfur; It provides the highest quality of MSM available, supporting amino acids and proteins in cartilage; This formula supports joint health
  • Sulfur Highlights: Sulfur is an antioxidant mineral found in the body’s structural proteins (i.e., chondroitin sulfate, dermatan sulfate and hyaluronic acid); Sulfur-containing structural proteins are in connective tissues like joint cartilage and skin
  • For Best Results: For best results, use with Jarrow Formulas JarroSil, the biologically Activated Silicon
  • Veggie Capsules: Take one veggie capsule one to three times per day or as directed by your qualified healthcare professional; This formula is suitable for vegans and vegetarians
  • Superior Nutrition and Formulation: The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements; Our customers can be assured of purity, value, and potency
#9 Real Supplements Rated Best in 2020
#10 Real Supplements Rated Best in 2020
Gold Standard Organic Sulfur Crystals 1lb - 99.9% Pure MSM Crystals - Largest Granular Flakes Available - 3rd Party Tested
3,759 Reviews
Gold Standard Organic Sulfur Crystals 1lb - 99.9% Pure MSM Crystals - Largest Granular Flakes Available - 3rd Party Tested
  • Quality and Purity: The Only Recommended Organosulfur Supplement by Independent Researchers. 99.9% Pure, Therapeutic-Grade Methylsulfonylmethane.
  • Value: Provides far more absorption power and effect than other crystals and 500-2000% more MSM than most pills, powder, or capsules.
  • Gold Standard: This is the original MSM in a gold bag, the original and Only Large Crystal Organic Sulfur - 99.9% Pure MSM.
  • The Gold Standard difference is the large size of our crystals and the unmatched absorption and potency. No other product matches in quality, size, purity, and absorption.
  • Top Notch Manufacturing: We start with Quality American Ingredients, not dirty petro chemicals. Double Distilled for Maximum Purity. We use low heat because overheating diminishes effectiveness. With our crystals, you get no fillers. No anti-caking additives. No binders. Our crystals are manufactured just for us in a facility with high oversight, hands-on, quality control.
#11 Real Supplements Rated Best in 2020
Glucosamine with Chondroitin Turmeric MSM Boswellia. Supports Occasional Joint Discomfort Relief. Helps Inflammatory Response, Antioxidant Properties. Supplement for Back, Knees, Hands. 90 Capsules
  • Why choose us: Discomfort in your joints? Vimerson Health Glucosamine may help increase your joints lubrication to assist with a smoother joint functionability* with this perfectly combined daily multivitamin and mineral supplement; Our blend promotes joint health and comfort*, helps support cartilage and joint flexibility*, encourages overall health*, and helps increase joint mobility*
  • Vimerson health ultra flex joint support is a complete dietary supplement for the joints; It may help build cartilage, boost joint mobility, increase joint flexibility, support joint structure, protect joint tissue and promote balanced inflammation;* Our product can help ease discomfort that come with age, weight or athletic deterioration of the joints in the body*
  • Great joints and cartilage support: Our Joint Health Formula is designed to maintain joint health and mobility;* The powerful nutrients in our formula may help to maintain joint flexibility;* Glucosamine, Chondroitin, Turmeric, MSM, Boswellia, Quercetin, Methionine and Bromelain are compounds that promote greater joint health and range of motion and comfort;* This effective Joint Complex works for Men Women and Seniors
  • Natural & non-GMO: Gluten free, dairy free, soy free, no soy, no sugar, no cholesterol, no artificial colors, flavors, no binders
  • Common names: There are many different ways people try and spell or pronounce Glucosamine and Chondroitin; Here are some common mis-spellings: glicosamina glucosamina glucosimine chondriton condroitan guclosamine glocosamin gucosamine glucoamine cosamine glucousimine glocosamina glucosamin gloucosamin glucosomine chondroitina condroitin condroitina chrondroitin condrotin chodroitin chondrotine chondroition condroiten chondoitin chondroitan condroiton chondritin chondroiton
#12 Real Supplements Rated Best in 2020
Life Extension MSM 1000 Mg, 100 Capsules
266 Reviews
Life Extension MSM 1000 Mg, 100 Capsules
  • MSM (methylsulfonylmethane or dimethylsulfone) is a sulfur-containing molecule found in various plants and some body tissues
  • MSM is a vital building block of joints, cartilage, skin, hair and nails. It is an efficient source of the sulfur that is used by many of the body’s structural molecules
  • Some peer-reviewed clinical research in the U.S. has shown MSM is safe and effective in increasing joint comfort and supporting a normal range of motion
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Sale#13 Real Supplements Rated Best in 2020
Nutramax Cosequin Equine Optimized with MSM, 1400 Gram Container
389 Reviews
Nutramax Cosequin Equine Optimized with MSM, 1400 Gram Container
  • Cosequin Optimized With Msm. Horse Feed Supplements
  • age range description: All Life Stages
  • For Horses Only
#14 Real Supplements Rated Best in 2020
Organic Sulfur Crystals, 99.9% Pure MSM Crystals, Premium MSM Supplement - 1 LBS Pack
  • PREMIUM QUALITY: Organic Sulfur Crystals Are Pure, High-Performance, Additive-Free MSM That Are Minimum of 99.9% Pure. The True, Premium Organo-Sulfur Supplement.
  • CERTIFIED PURITY: A minimum of 99.9% Pure MSM. ZERO Fillers. ZERO Additives. ZERO Binders. Every Batch Is 3rd-Party, Independent Lab Certified For Premium Quality & Purity. Also Tested For Heavy Metals & VOC's. Manufactured In an FDA Registered Facility. Naturally Gluten & GMO Free, Vegan Friendly.
  • EXCELLENT VALUE: Provides an Avg. of 500% - 2000% More MSM Per Serving Than In Most Pills Powders Or Joint Formulations. Each Bag Provides 45 - 90 Days of Supply / 90.8 metric teaspoon servings per bag.
  • EASY TO USE: Simply Take a 1/4 to 1/2 Teaspoon To Start - Or As Directed By Your Health Practitioner - Morning And Night With Some Water Or Juice.
  • 100% SATISFACTION GUARANTEED. It can help, or return it for a full refund - Simple. **Don't Pay Up To 30% More For "Larger Crystals". All MSM Crystals That Are Pure & Additive-Free Provide Similar Strength & Absorption - So Why Pay More For Larger Crystals That Just Take Longer To Dissolve?
#15 Real Supplements Rated Best in 2020
Kala Health MSMPure Coarse Powder Flakes, Organic Sulfur Crystals, 99.9% Pure Distilled MSM Supplement, Made in The USA, 1lb
4,330 Reviews
Kala Health MSMPure Coarse Powder Flakes, Organic Sulfur Crystals, 99.9% Pure Distilled MSM Supplement, Made in The USA, 1lb
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Sale#16 Real Supplements Rated Best in 2020
Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Caps (DRB-00064)
1,327 Reviews
Doctor's Best MSM with OptiMSM, Joint Support, Immune System, Antioxidant and Protein-Building Role, Non-GMO, Gluten Free, 1000 mg, 180 Caps (DRB-00064)
  • DOCTOR’S BEST MSM FEATURES OPTIMSM: with OptiMSM a high quality purified MSM (methylsulfonylmethane) backed by numerous clinical studies for safety and efficacy. MSM is a natural sulfur compound that helps support the formation of healthy connective tissues. It also helps support overall joint mobility, and a normal range of motion.
  • BENEFITS TO JOINTS: MSM is a natural sulfur that helps form the antioxidants N-acetylcysteine and glutathione and serves as a key structural nutrient in healthy joints. Improves joint function and helps protect cartilage, mobility, reduces joint pain, increases range of motion.
  • IMMUNE SUPPORT: MSM provides support for immune function, and for the body’s antioxidant and overall protective capacities resulting in a stronger immune response.
  • NATURE’S BEAUTY MINERAL: MSM provides sulfur and is often called “nature’s beauty mineral”. Sulfur restores collagen production that supports healthy skin and is a building block of keratin, an essential protein for improving skin, hair and nails.
  • CLINICAL STUDIES: Sulfur continues to be an important dietary nutrient to support healthy aging. With its regulation of glutathione and other ways in the body, MSM can help support healthy skin, joint mobility, cartilage, and the antioxidant response.
Sale#17 Real Supplements Rated Best in 2020
Jarrow Formulas Glucosamine + Chondroitin + MSM - 240 Capsules - Nutrient Support of Joint Health - With Vitamin C & Manganese - 60 Servings
984 Reviews
Jarrow Formulas Glucosamine + Chondroitin + MSM - 240 Capsules - Nutrient Support of Joint Health - With Vitamin C & Manganese - 60 Servings
  • Glucosamine & Chondroitin - Glucosamine and chondroitin sulfate are components of hyaluronic acid in joint cartilage and synovial fluid. This formula supplies nutrient support of joint health.
  • MSM - Methylsulfonylmethane (MSM) is an organic source of sulfur, an antioxidant mineral, and component of structural body tissues, such as cartilage.
  • With Vitamin C & Manganese - Vitamin C and manganese support the synthesis of collagen and cartilage.
  • Convenient Capsules - Take four capsules per day or as directed by your qualified healthcare professional. The formula is sodium-free and stabilized with potassium chloride (KCI).
  • Superior Nutrition & Formulation - The goal of Jarrow Formulas is to promote optimal health with high-quality, effective, affordable, and superior formulation of dietary supplements. Our customers can be assured of purity, value, and potency.
#18 Real Supplements Rated Best in 2020
365 by WFM, MSM 1000Mg, 90 Tablets
101 Reviews
365 by WFM, MSM 1000Mg, 90 Tablets
  • 365 by Whole Foods Market products give you that dance-down-the-aisles feeling, virtual aisles too! Our huge range of choices with premium ingredients at prices you can get down with makes grocery shopping so much more than tossing the basics in your cart.
#19 Real Supplements Rated Best in 2020
Puritans Pride Triple Strength Glucosamine, Chondroitin and Msm Joint Soother, 360 Count
2,861 Reviews
Puritans Pride Triple Strength Glucosamine, Chondroitin and Msm Joint Soother, 360 Count
  • Highest quality vitamins and supplements since 1973
  • Contains 3 popular ingredients that support joint and cartilage health
  • Supports mobility and flexibility for comfortable movement
  • Gluten & Soy Free
  • 6 month supply
#20 Real Supplements Rated Best in 2020
Now MSM 1000 mg, 400 Veg Capsules, Methylsulphonylmethane
301 Reviews
Now MSM 1000 mg, 400 Veg Capsules, Methylsulphonylmethane
  • ✅ NOW FOODS MSM 1000mg: Methylsulphonylmethane is a natural form of organic sulfur found in all living organisms
  • ✅ HEAL YOUR BODY TISSUES: Supports Healthy Cartilage* and for Connective Tissue*. This natural compound provides the chemical links needed to form and maintain many types of tissues found in human body, including connective tissues.
  • ✅ PURITY ASSURANCE: NOW MSM is tested to meet a minimum 99.7% purity
  • ✅ NEW AND IMPROVED CAPS: Capsules are now Vegan / Vegetarian
  • ✅ Made in the USA

Top 10 Health Benefits of MSM

Methylsulfonylmethane, more commonly known as MSM, is a popular dietary supplement used to treat a wide array of symptoms and conditions. MSM is an organic Sulfur compound and Sulfur is in over 150 different compounds in our body and there are virtually sulfur compounds in every body cell. In addition Sulfur improves our body’s capability to produce its own antioxidants.
Sulfur is one of the most important nutrients for our body, to help maintain youthful and energetic. With the increasing interest in anti-aging products, MSM has become more known for the amazing benefits it contains as listed below.

1. Improves skin, hair, and nail health and complexion

MSM contains large amounts of Sulfur (S), which is necessary for collagen and keratin production and they are both vital for healthy skin, hair, and nail. MSM and Vitamin C together build new and healthy tissues and can normalize collagen formation and could improve skin, hair, and nail healthy drastically and that’s why MSM is often referred as “Beauty Mineral”. MSM can enhance the thickness and strength of hair and nails in a very short time. Also, research shows that MSM is very effective in the treatment of some skin conditions such as:
Psoriasis
Eczema
Rosacea
Dermatitis
Acne
Dandruff

2. Bone and joint care

MSM is a necessary nutrient in our bone and joint health, which helps conditions such as arthritis, rheumatoid arthritis, and osteoarthritis. Also, MSM increases capability of our body to break up unhealthy Calcium (Ca) deposits in our body that are the main reason for degenerative diseases.
Another benefit of MSM is joint flexibility, flexible skin and muscle tissue. In addition, MSM reduces pain, swelling, and stiffness.

3. Detoxifies the body

MSM is highly effective in increasing the ability of cells to flush out excess fluids and toxins, which is also known as “permeability”. By flushing out toxins from the cells, there is room created for essential nutrients and hydration to move in and this process improves the overall functionality of your cell membranes, which have the main task of protecting the cells from its surroundings.
In addition, MSM helps the body get rid of lactic acid and other toxins that cause pain and soreness . This will also provide more energy in our body, which we talk about in more detail in next paragraph.

4. Naturally Increases energy

Another benefit of higher permeability is better efficiency. Since the cells flush out the toxins and don’t have to deal with that. Therefore, they use less energy to deal with toxins and have more energy to use towards other activities such as digestion and healing. In addition, our body spends anywhere between 60-80% of its energy to digest food everyday and due to detoxification process it becomes easier to digest food and absorb nutrients. Moreover, our cells become more efficient and wastes less energy in unnecessary activities and because of that there are some more benefits for having more efficient body such as:
Improves conditions such asthma and allergies
Improve our body pH level and makes our body more alkaline
Helps cure gastrointestinal issues such as diarrhea, nausea, constipation and hyperacidity
Improves conditions like cramps and muscular pain, especially in athletes
Heals carpal tunnel syndrome
Balances your blood sugar
Reduces overall stress levels

TOP 10 Benefits

1. Can Decrease Joint Pain, Which Could Improve Your Quality of Life
One of the most popular uses of MSM is to decrease joint or muscle pain.

It has been shown to benefit those with joint degeneration, a common cause of pain in the knees, back, hands and hips.

Joint degeneration can negatively impact your quality of life by limiting your movement and mobility.

Studies have shown that MSM significantly reduces inflammation in your body. It also inhibits the breakdown of cartilage, a flexible tissue that protects the ends of your bones in joints.

A study in 100 people over the age of 50 found that treatment with a supplement containing 1,200 mg of MSM for 12 weeks decreased pain, stiffness and swelling in the joints, compared to a placebo.

The group receiving the supplement also reported improved overall quality of life and less difficulty walking and getting out of bed.

Another study in 32 people with lower back pain found that taking a glucosamine supplement containing MSM significantly reduced lumbar stiffness and pain upon movement, plus greatly increased quality of life.

SUMMARY
Studies have shown that MSM is effective in reducing joint pain, stiffness and swelling. In doing so, it can improve your quality of life.
2. Has Anti-Inflammatory Effects, Such as Increasing Glutathione Levels
The anti-inflammatory properties of MSM are well documented by scientific research.

It’s believed that MSM inhibits NF-kB, a protein complex involved in inflammatory responses in your body.

It also reduces the production of cytokines such as tumor necrosis factor alpha (TNF-ɑ) and interleukin 6 (IL-6), which are signaling proteins linked to systemic inflammation.

Additionally, MSM can increase levels of glutathione, a potent antioxidant produced by your body.

For example, supplementing with MSM significantly reduced inflammation in mice with stomach ulcers by inhibiting the release of inflammatory cytokines including TNF-ɑ and IL-6, as well as increasing glutathione levels.

Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo.

SUMMARY
MSM may reduce the release of molecules associated with inflammation, such as TNF-ɑ and IL-6, as well as boost levels of the powerful antioxidant glutathione.

3. Can Speed Recovery After Exercise by Reducing Muscle Damage and Stress
During exhaustive exercise, muscle damage occurs and oxidative stress increases.

This causes athletes to experience muscle soreness and pain, which can hinder athletic performance and training.

MSM can naturally speed muscle recovery after intense exercise by reducing inflammation and oxidative stress.

A study in 18 men showed that taking 50 mg of MSM powder per kg of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity following an 8.7 mile (14 km) run.

It may also be beneficial for reducing pain after prolonged exercise.

In one study, 22 healthy women received 3 grams of MSM or a placebo per day for three weeks leading up to a half marathon. The MSM group reported less muscle soreness and joint pain than the placebo group.

Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise.

SUMMARY
MSM may help reduce pain, muscle damage and oxidative stress after intense exercise, helping you recover more quickly.
4. Helps Alleviate Arthritis Symptoms by Reducing Pain and Stiffness
Arthritis is a common inflammatory condition that causes pain, stiffness and a reduced range of motion in your joints.

Since MSM has powerful anti-inflammatory properties, it’s often used as a natural alternative to medications to improve arthritis-related symptoms.

A study in 49 people with knee osteoarthritis found that taking 3.4 grams of MSM per day for 12 weeks reduced pain and stiffness and improved physical function, compared to a placebo.

Additionally, it can enhance the effectiveness of other common supplements used to treat arthritis such as glucosamine sulfate, chondroitin sulfate and boswellic acid.

One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone.

Another study showed that a daily supplement containing 5 grams of MSM and 7 grams of boswellic acid was more effective than glucosamine at reducing pain and improving function in people with knee osteoarthritis.

What’s more, the people who received the MSM and boswellic acid supplement were less dependent on anti-inflammatory medications than the glucosamine group.

SUMMARY
MSM supplements have been shown to help reduce pain and stiffness in people with arthritis. They may also help improve physical function.

5. May Help Relieve Allergy Symptoms by Reducing Inflammation
Allergic rhinitis is an allergic reaction that causes symptoms such as watery eyes, sneezing, itching, runny nose and nasal congestion.

Common triggers of allergic rhinitis include animal dander, pollen and molds.

After exposure to an allergen, many inflammatory substances such as prostaglandins and cytokines are released, which leads to unpleasant symptoms.

Studies have shown that MSM may be effective in reducing symptoms of allergic rhinitis.

It may decrease allergic reactions by lowering inflammation and inhibiting the release of cytokines and prostaglandins.

A study in 50 people with allergic rhinitis found that a dose of 2,600 mg of MSM per day over 30 days reduced symptoms including itching, congestion, shortness of breath, sneezing and coughing.

Additionally, participants experienced a significant increase in energy by day 14.

SUMMARY
MSM may help reduce allergy-related symptoms — including coughing, shortness of breath, congestion, sneezing and fatigue — by reducing inflammation.
6. Can Boost Immunity and Help You Stay Healthy
Your immune system is a specialized network of tissues, cells and organs that protects your body against illness and disease.

It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity.

Sulfur compounds such as MSM play important roles in the health of your immune system.

For example, MSM may be effective in reducing oxidative stress and inflammation that can weaken immunity. Since it’s effective in reducing levels of inflammatory compounds like IL-6 and TNF-ɑ, MSM may reduce stress on your immune system.

Additionally, it plays a part in the creation of glutathione, your body’s master antioxidant. It may also help increase levels of this important compound.

Having adequate levels of glutathione is crucial for the overall health and function of your immune system.

A test-tube study showed that MSM effectively restored glutathione levels and reduced inflammatory markers in mouse cells that had been weakened with HIV proteins.

SUMMARY
MSM may help boost your immune system by reducing inflammation and increasing glutathione levels.

7. Could Improve Skin Health by Strengthening Keratin
Keratin is a protein that acts as the main structural component in your hair, skin and nails.

It contains high levels of the sulfur-containing amino acid cysteine. That’s why burnt hair gives off a characteristic sulfurous smell.

MSM may be beneficial for skin health by acting as a sulfur donor to keratin. This, in turn, can help strengthen this important protein.

MSM also helps reduce inflammation, which can damage skin cells and cause signs of premature aging like wrinkles.

It may even reduce symptoms of problematic skin conditions such as rosacea, which can cause redness, irritation and inflammation of the skin.

One study showed that, when applied to the skin, MSM significantly improved redness, itching, inflammation, hydration and skin color in people with rosacea.

SUMMARY
MSM may improve skin health by strengthening keratin and reducing inflammation. It could even help reduce symptoms of certain skin conditions, as well.
8. May Have Cancer-Fighting Properties
One of the newest areas of research involving MSM is studying its effectiveness in fighting cancer cells. Although the research is limited, the results have been promising so far.

Several test-tube studies have shown that MSM inhibits the growth of stomach, esophageal, liver, colon, skin and bladder cancer cells .

It seems to do this by damaging cancer cell DNA and stimulating cancer cell death.

MSM also appears to prevent the spread of cancer cells, also known as metastasis.

A study in mice with liver cancer showed that those injected with MSM had fewer tumors, smaller tumor size and less liver damage than those who did not receive the treatment.

Another mouse study demonstrated that MSM inhibited the growth of human breast cancer cells.

Although these results are encouraging, more research is needed to determine the safety and efficacy of using MSM in cancer treatment.

SUMMARY
Research has shown that MSM exhibits cancer-fighting properties in test-tube and animal studies, but more research is needed.

MSM Safety and Side Effects
MSM is considered safe and is generally well tolerated with minimal side effects.

Major regulatory agencies such as the FDA have given it the Generally Recognized As Safe (GRAS) designation.

Numerous toxicity studies have been done to assess the safety of MSM and doses up to 4,845.6 mg per day (4.8 grams) appear to be safe.

However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhea. When applied to the skin, it may also cause mild skin or eye irritation.

Additionally, there is concern over mixing MSM with alcohol since other sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages.

However, no studies have explored this potentially problematic combination yet.

SUMMARY
MSM supplements are generally considered safe. However, they may cause side effects like nausea, diarrhea and skin reactions in some people.
The Bottom Line
MSM is a popular supplement with a wide variety of uses.

Research shows that it may be helpful in reducing joint pain, lowering inflammation, improving skin health, decreasing allergy symptoms and speeding recovery after exercise.

Additionally, some evidence suggests that MSM can boost the immune system and may have cancer-fighting properties.

MSM appears to be safe and studies report only minimal side effects.

Although the current findings on MSM are promising, more research is needed to understand all of its potential benefits as well as possible side effects.


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