MSM

Helps form bridges that shape and stabilize some protein structures. Needed for healthy hair, skin, and nails.

Top MSM

Best Seller No. 1
NOW Supplements, MSM (Methylsulfonylmethane)1000 mg, 240 Veg Capsules
472 Reviews
NOW Supplements, MSM (Methylsulfonylmethane)1000 mg, 240 Veg Capsules
  • JOINT SULFUR FOR CONNECTIVE TISSUE*: MSM, in its role in the body's sulfur cycle, helps to create the chemical links needed to form and maintain numerous different types of structural tissues of the human body, including connective tissues, such as articular cartilage and skin.*
  • VEGAN CAPSULES/SUPPORTS HEALTHY CARTILAGE*: Sulfur compounds are found in all body cells and are indispensable for life.*
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Dairy Free, Egg Free, Made without Gluten, Corn Free, Soy Free, Kosher, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968
Best Seller No. 2
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1000 mg Caps, 360Count
144 Reviews
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1000 mg Caps, 360Count
  • Doctor's Best MSM promotes joint comfort and mobility by helping maintenance of healthy connective tissue
  • OptiMSM, the source of MSM used in Doctor's Best, is a patented, highly purified form of MSM
  • MSM helps keep skin, hair and nails healthy by promoting the production of keratin
  • Doctor's Best MSM is available in tablet, powder, capsule and veggie cap forms supplying 250g to 1500mg MSM per serving
  • Non-GMO and Gluten Free
SaleBest Seller No. 3
Jarrow Formulas MSM, A Bioavailable Source of Sulfur, with Antioxidant and Protein-Building Functions*, 1000 mg, 200 Veggie Capsules
366 Reviews
Jarrow Formulas MSM, A Bioavailable Source of Sulfur, with Antioxidant and Protein-Building Functions*, 1000 mg, 200 Veggie Capsules
  • A Bioavailable Source of Sulfur, with Antioxidant and Protein-Building Functions*
  • Provides the Highest Quality MSM Available
  • An Important Source of Organic Sulfur During Times of Stress, Toxicity, and Repair*
  • An Organic Source of Sulfur Shown to be Incorporated MSM into Amino Acids and Proteins Involved in Cartilage Formation and Detoxification*
Best Seller No. 5
Now Supplements, MSM (Methylsulfonylmethane)1500 mg, 200 Tablets
242 Reviews
Now Supplements, MSM (Methylsulfonylmethane)1500 mg, 200 Tablets
  • Methylsulphonylmethane
  • For Connective Tissue
  • For Healthy Cartilage
SaleBest Seller No. 6
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1000 mg, 180 Caps
194 Reviews
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1000 mg, 180 Caps
  • Doctor's Best MSM promotes joint comfort and mobility by helping maintenance of healthy connective tissue
  • OptiMSM, the source of MSM used in Doctor's Best, is a patented, highly purified form of MSM
  • MSM helps keep skin, hair and nails healthy by promoting the production of keratin
  • Doctor's Best MSM is available in tablet, powder, capsule and veggie cap forms supplying 250g to 1500mg MSM per serving
  • Non-GMO and Gluten Free
Best Seller No. 7
Kala Health MSMPure Coarse Powder Flakes, Organic Sulfur Crystals, 99.9% Pure Distilled MSM Supplement, Made in The USA, 8.8 oz
  • WHY MSMPure POWDER? We only use Optimsm which is “the purest MSM on the Planet” and the only MSM made in the USA. Our MSM is the organic form of naturally occurring Sulfur. MSMPure goes through a propriety multi-stage distillation process that ensures a 99.9% pure, third party tested to meet our stringent product specifications. This is the only GRAS-designated, Kosher & Halal certified, non-GMO, gluten-free, allergen-free, non-shellfish-derived, vegan MSM backed by extensive toxicology data.
  • WHAT ARE MSMPure BENEFITS TO JOINTS? Improves joint function and mobility, Reduces joint pain and stiffness, Increases range of motion, Protects cartilage, Decreases swelling and inflammation, Aids in short term recovery by reducing inflammatory responses and swelling involved in joint pain and fatigue.
  • MSMPure IS COMMONLY USED NATURALLY FOR MEN AND WOMEN WITH: Any of the following joints or ligaments pain: shoulder, hands, fingers, wrist, ankles, heel, knees, hip, lumbar back, lower back or foot or chronic arthritis, rheumatoid arthritis, plantar fasciitis, bursitis, tendinitis, tennis elbow, trigger finger, hair growth, nail growth.
  • MSMPure ADDITIONAL BENEFITS: Known as "Nature's Beauty Mineral" for faster hair growth, promote nail growth, improve skin texture, younger looking skin, may reduce fine lines and wrinkles, restores collagen production and acne improvement.
  • The MSMPure GUARANTEE: No-Risk 100% Satisfaction Guarantee if you for any reason do not feel MSM is helping you. At Kala Health we stand behind every product we manufacture for our customers.
Best Seller No. 8
Doctor's Best Glucosamine Chondroitin Msm with OptiMSM Capsules, Supports Healthy Joint Structure, Function & Comfort, Non-GMO, Gluten Free, Soy Free, 240 Count (Pack of 1)
1,837 Reviews
Doctor's Best Glucosamine Chondroitin Msm with OptiMSM Capsules, Supports Healthy Joint Structure, Function & Comfort, Non-GMO, Gluten Free, Soy Free, 240 Count (Pack of 1)
  • Glucosamine/chondroitin/MSM with optimism: the ultimate combination for healthy joints! Glucosamine supplements are used to help prevent the breakdown of joint tissues and any associated symptoms including pain, lack of flexion, joint stiffness and weakness. Chondroitin helps keep joints healthy by absorbing fluid (particularly water) in the bones. Msm provides a source of dietary sulfur and half of the body’s sulfur is found in the skin, muscles, and bones. Sulfur is a critical building blocker, strengthens joint tissues and helps with elasticity.*
  • Improve joint flexibility: a potent combination of three proven, purified ingredients that help build and serves as a shock absorber for your joints. Healthy joints may get worn away by sports injuries, overuse, or wear-and-tear that can cause joint discomfort.*
  • Benefits of glucosamine/chondroitin/MSM with optimism: helps supports joint mobility, joint structure, and can increase joint flexibility while protecting joint tissue. Also supports overall health for hair, skin, and nails.*
  • Clinically-studied optimism: Glucosamine/chondroitin/MSM with optimism clinically proven, purified ingredients to improve joint function and mobility, combined into one supplement. Provides you with the perfect combination of potent dietary supplements that will help you maintain and support your joint healthy throughout your active Lifetime.*
Best Seller No. 9
BulkSupplements MSM (Methysulfonylmethane) Powder (1 Kilogram)
1,916 Reviews
BulkSupplements MSM (Methysulfonylmethane) Powder (1 Kilogram)
  • Clean & pure powder. No fillers.
  • Lab tested for verification & guaranteed purity
  • Factory-sealed foil zip pouch
  • Promotes joint health
  • Role in collagen formation
Best Seller No. 10
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1500 mg, 120 Tablets
575 Reviews
Doctor's Best MSM with OptiMSM, Non-GMO, Gluten Free, Joint Support, 1500 mg, 120 Tablets
  • Doctor's Best MSM promotes joint comfort and mobility by helping maintenance of healthy connective tissue
  • OptiMSM, the source of MSM used in Doctor's Best, is a patented, highly purified form of MSM
  • MSM helps keep skin, hair and nails healthy by promoting the production of keratin
  • Doctor's Best MSM is available in tablet, powder, capsule and veggie cap forms supplying 250g to 1500mg MSM per serving
  • Non-GMO and Gluten Free

Top 10 Health Benefits of MSM

Methylsulfonylmethane, more commonly known as MSM, is a popular dietary supplement used to treat a wide array of symptoms and conditions. MSM is an organic Sulfur compound and Sulfur is in over 150 different compounds in our body and there are virtually sulfur compounds in every body cell. In addition Sulfur improves our body’s capability to produce its own antioxidants.
Sulfur is one of the most important nutrients for our body, to help maintain youthful and energetic. With the increasing interest in anti-aging products, MSM has become more known for the amazing benefits it contains as listed below.

1. Improves skin, hair, and nail health and complexion

MSM contains large amounts of Sulfur (S), which is necessary for collagen and keratin production and they are both vital for healthy skin, hair, and nail. MSM and Vitamin C together build new and healthy tissues and can normalize collagen formation and could improve skin, hair, and nail healthy drastically and that’s why MSM is often referred as “Beauty Mineral”. MSM can enhance the thickness and strength of hair and nails in a very short time. Also, research shows that MSM is very effective in the treatment of some skin conditions such as:
Psoriasis
Eczema
Rosacea
Dermatitis
Acne
Dandruff

2. Bone and joint care

MSM is a necessary nutrient in our bone and joint health, which helps conditions such as arthritis, rheumatoid arthritis, and osteoarthritis. Also, MSM increases capability of our body to break up unhealthy Calcium (Ca) deposits in our body that are the main reason for degenerative diseases.
Another benefit of MSM is joint flexibility, flexible skin and muscle tissue. In addition, MSM reduces pain, swelling, and stiffness.

3. Detoxifies the body

MSM is highly effective in increasing the ability of cells to flush out excess fluids and toxins, which is also known as “permeability”. By flushing out toxins from the cells, there is room created for essential nutrients and hydration to move in and this process improves the overall functionality of your cell membranes, which have the main task of protecting the cells from its surroundings.
In addition, MSM helps the body get rid of lactic acid and other toxins that cause pain and soreness . This will also provide more energy in our body, which we talk about in more detail in next paragraph.

4. Naturally Increases energy

Another benefit of higher permeability is better efficiency. Since the cells flush out the toxins and don’t have to deal with that. Therefore, they use less energy to deal with toxins and have more energy to use towards other activities such as digestion and healing. In addition, our body spends anywhere between 60-80% of its energy to digest food everyday and due to detoxification process it becomes easier to digest food and absorb nutrients. Moreover, our cells become more efficient and wastes less energy in unnecessary activities and because of that there are some more benefits for having more efficient body such as:
Improves conditions such asthma and allergies
Improve our body pH level and makes our body more alkaline
Helps cure gastrointestinal issues such as diarrhea, nausea, constipation and hyperacidity
Improves conditions like cramps and muscular pain, especially in athletes
Heals carpal tunnel syndrome
Balances your blood sugar
Reduces overall stress levels

TOP 10 Benefits

1. Can Decrease Joint Pain, Which Could Improve Your Quality of Life
One of the most popular uses of MSM is to decrease joint or muscle pain.

It has been shown to benefit those with joint degeneration, a common cause of pain in the knees, back, hands and hips.

Joint degeneration can negatively impact your quality of life by limiting your movement and mobility.

Studies have shown that MSM significantly reduces inflammation in your body. It also inhibits the breakdown of cartilage, a flexible tissue that protects the ends of your bones in joints.

A study in 100 people over the age of 50 found that treatment with a supplement containing 1,200 mg of MSM for 12 weeks decreased pain, stiffness and swelling in the joints, compared to a placebo.

The group receiving the supplement also reported improved overall quality of life and less difficulty walking and getting out of bed.

Another study in 32 people with lower back pain found that taking a glucosamine supplement containing MSM significantly reduced lumbar stiffness and pain upon movement, plus greatly increased quality of life.

SUMMARY
Studies have shown that MSM is effective in reducing joint pain, stiffness and swelling. In doing so, it can improve your quality of life.
2. Has Anti-Inflammatory Effects, Such as Increasing Glutathione Levels
The anti-inflammatory properties of MSM are well documented by scientific research.

It’s believed that MSM inhibits NF-kB, a protein complex involved in inflammatory responses in your body.

It also reduces the production of cytokines such as tumor necrosis factor alpha (TNF-ɑ) and interleukin 6 (IL-6), which are signaling proteins linked to systemic inflammation.

Additionally, MSM can increase levels of glutathione, a potent antioxidant produced by your body.

For example, supplementing with MSM significantly reduced inflammation in mice with stomach ulcers by inhibiting the release of inflammatory cytokines including TNF-ɑ and IL-6, as well as increasing glutathione levels.

Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo.

SUMMARY
MSM may reduce the release of molecules associated with inflammation, such as TNF-ɑ and IL-6, as well as boost levels of the powerful antioxidant glutathione.

3. Can Speed Recovery After Exercise by Reducing Muscle Damage and Stress
During exhaustive exercise, muscle damage occurs and oxidative stress increases.

This causes athletes to experience muscle soreness and pain, which can hinder athletic performance and training.

MSM can naturally speed muscle recovery after intense exercise by reducing inflammation and oxidative stress.

A study in 18 men showed that taking 50 mg of MSM powder per kg of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity following an 8.7 mile (14 km) run.

It may also be beneficial for reducing pain after prolonged exercise.

In one study, 22 healthy women received 3 grams of MSM or a placebo per day for three weeks leading up to a half marathon. The MSM group reported less muscle soreness and joint pain than the placebo group.

Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise.

SUMMARY
MSM may help reduce pain, muscle damage and oxidative stress after intense exercise, helping you recover more quickly.
4. Helps Alleviate Arthritis Symptoms by Reducing Pain and Stiffness
Arthritis is a common inflammatory condition that causes pain, stiffness and a reduced range of motion in your joints.

Since MSM has powerful anti-inflammatory properties, it’s often used as a natural alternative to medications to improve arthritis-related symptoms.

A study in 49 people with knee osteoarthritis found that taking 3.4 grams of MSM per day for 12 weeks reduced pain and stiffness and improved physical function, compared to a placebo.

Additionally, it can enhance the effectiveness of other common supplements used to treat arthritis such as glucosamine sulfate, chondroitin sulfate and boswellic acid.

One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone.

Another study showed that a daily supplement containing 5 grams of MSM and 7 grams of boswellic acid was more effective than glucosamine at reducing pain and improving function in people with knee osteoarthritis.

What’s more, the people who received the MSM and boswellic acid supplement were less dependent on anti-inflammatory medications than the glucosamine group.

SUMMARY
MSM supplements have been shown to help reduce pain and stiffness in people with arthritis. They may also help improve physical function.

5. May Help Relieve Allergy Symptoms by Reducing Inflammation
Allergic rhinitis is an allergic reaction that causes symptoms such as watery eyes, sneezing, itching, runny nose and nasal congestion.

Common triggers of allergic rhinitis include animal dander, pollen and molds.

After exposure to an allergen, many inflammatory substances such as prostaglandins and cytokines are released, which leads to unpleasant symptoms.

Studies have shown that MSM may be effective in reducing symptoms of allergic rhinitis.

It may decrease allergic reactions by lowering inflammation and inhibiting the release of cytokines and prostaglandins.

A study in 50 people with allergic rhinitis found that a dose of 2,600 mg of MSM per day over 30 days reduced symptoms including itching, congestion, shortness of breath, sneezing and coughing.

Additionally, participants experienced a significant increase in energy by day 14.

SUMMARY
MSM may help reduce allergy-related symptoms — including coughing, shortness of breath, congestion, sneezing and fatigue — by reducing inflammation.
6. Can Boost Immunity and Help You Stay Healthy
Your immune system is a specialized network of tissues, cells and organs that protects your body against illness and disease.

It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity.

Sulfur compounds such as MSM play important roles in the health of your immune system.

For example, MSM may be effective in reducing oxidative stress and inflammation that can weaken immunity. Since it’s effective in reducing levels of inflammatory compounds like IL-6 and TNF-ɑ, MSM may reduce stress on your immune system.

Additionally, it plays a part in the creation of glutathione, your body’s master antioxidant. It may also help increase levels of this important compound.

Having adequate levels of glutathione is crucial for the overall health and function of your immune system.

A test-tube study showed that MSM effectively restored glutathione levels and reduced inflammatory markers in mouse cells that had been weakened with HIV proteins.

SUMMARY
MSM may help boost your immune system by reducing inflammation and increasing glutathione levels.

7. Could Improve Skin Health by Strengthening Keratin
Keratin is a protein that acts as the main structural component in your hair, skin and nails.

It contains high levels of the sulfur-containing amino acid cysteine. That’s why burnt hair gives off a characteristic sulfurous smell.

MSM may be beneficial for skin health by acting as a sulfur donor to keratin. This, in turn, can help strengthen this important protein.

MSM also helps reduce inflammation, which can damage skin cells and cause signs of premature aging like wrinkles.

It may even reduce symptoms of problematic skin conditions such as rosacea, which can cause redness, irritation and inflammation of the skin.

One study showed that, when applied to the skin, MSM significantly improved redness, itching, inflammation, hydration and skin color in people with rosacea.

SUMMARY
MSM may improve skin health by strengthening keratin and reducing inflammation. It could even help reduce symptoms of certain skin conditions, as well.
8. May Have Cancer-Fighting Properties
One of the newest areas of research involving MSM is studying its effectiveness in fighting cancer cells. Although the research is limited, the results have been promising so far.

Several test-tube studies have shown that MSM inhibits the growth of stomach, esophageal, liver, colon, skin and bladder cancer cells .

It seems to do this by damaging cancer cell DNA and stimulating cancer cell death.

MSM also appears to prevent the spread of cancer cells, also known as metastasis.

A study in mice with liver cancer showed that those injected with MSM had fewer tumors, smaller tumor size and less liver damage than those who did not receive the treatment.

Another mouse study demonstrated that MSM inhibited the growth of human breast cancer cells.

Although these results are encouraging, more research is needed to determine the safety and efficacy of using MSM in cancer treatment.

SUMMARY
Research has shown that MSM exhibits cancer-fighting properties in test-tube and animal studies, but more research is needed.

MSM Safety and Side Effects
MSM is considered safe and is generally well tolerated with minimal side effects.

Major regulatory agencies such as the FDA have given it the Generally Recognized As Safe (GRAS) designation.

Numerous toxicity studies have been done to assess the safety of MSM and doses up to 4,845.6 mg per day (4.8 grams) appear to be safe.

However, some people may experience mild reactions if they are sensitive to MSM, such as stomach issues like nausea, bloating and diarrhea. When applied to the skin, it may also cause mild skin or eye irritation.

Additionally, there is concern over mixing MSM with alcohol since other sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages.

However, no studies have explored this potentially problematic combination yet.

SUMMARY
MSM supplements are generally considered safe. However, they may cause side effects like nausea, diarrhea and skin reactions in some people.
The Bottom Line
MSM is a popular supplement with a wide variety of uses.

Research shows that it may be helpful in reducing joint pain, lowering inflammation, improving skin health, decreasing allergy symptoms and speeding recovery after exercise.

Additionally, some evidence suggests that MSM can boost the immune system and may have cancer-fighting properties.

MSM appears to be safe and studies report only minimal side effects.

Although the current findings on MSM are promising, more research is needed to understand all of its potential benefits as well as possible side effects.


Real Supplements gives you the best MSM on the market today. Our top-rated lists are fresh and current so you get the best options.

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Amazon Best Seller Products List Last Updated on 2019-11-20