Niacin (Vitamin B3)

  • Maintains lipid levels
  • Promotes healthy skin
  • Prevents cognitive impairments
  • Treats diabetes
  • Prevents pellagra
  • Relieves arthritis
  • Prevents birth defects
  • Treats erectile dysfunction
  • Relieves motion sickness
  • Aids in digestion

Best Niacin

Sale#1 Real Supplements Rated Best in 2020
Nature's Bounty Niacin 500mg Flush Free, Cellular Energy Support, Supports Nervous System Health, 120 Capsules
  • CELLULAR ENERGY SUPPORT (1): Niacin, also known as Vitamin B3, is found naturally in foods such as beef, avocados and potatoes and aids in the conversion of food to cellular energy. (1) Nature’s Bounty Niacin offers the energy cellular support you need to fuel your body (1)
  • FLUSH FREE FORMULA: Niacin not only has a wide range of health supporting benefits, but our flush free formula uses Inositol Hexanicotinate, a form of Niacin that is less likely to cause skin flushing
  • SUPPORTS NERVOUS SYSTEM HEALTH (1): Along with providing daily cellular energy support, Niacin supports nervous system health. (1) If you need a daily nervous system supplement, consider adding Nature’s Bounty Niacin to your routine (1)
  • FROM THE TRUSTED WELLNESS EXPERTS: Nature’s Bounty Niacin is a product of 50 years of dedication to quality, consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence
  • EXCELLENT VALUE COMPARED WITH OTHER TOP BRANDS: Compare Nature’s Bounty products to Bixa Botanical, Na'trition, Women’s Health Network, Organic India, Vimerson Health, Zhou, New Chapter, Baetea, Nature’s Way, BioScience Nutrition, Nature’s Secret, Bio Schwartz, Health Concerns, Nested, Havasu, and OHCO
Sale#2 Real Supplements Rated Best in 2020
NOW Supplements, Niacin (Vitamin B-3) 500 mg, Sustained Release, Nutritional Health, 250 Tablets
  • NIACIN 500 mg TABLETS/VITAMIN B-3: Niacin (Vitamin B-3) is an essential B-group vitamin necessary for good health.
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • SUSTAINED RELEASE TO MINIMIZE FLUSHING: Niacin supplements may sometimes temporarily cause flushing and/or itching, but this sustained release tablet should minimize those symptoms. To further limit these uncomfortable but not dangerous symptoms, take daily and avoid missing doses.
  • CERTIFICATIONS/CLASSIFICATIONS: Soy Free, Made without Gluten, Dairy Free, Egg Free, Nut Free, Kosher, Vegan/Vegetarian
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
Sale#3 Real Supplements Rated Best in 2020
Nutricost Niacin (Vitamin B3) 500mg, 240 Capsules - with Flushing, Non-GMO, Gluten Free
  • Potent 500mg of Niacin (Vitamin B3) Per Capsule
  • Warning: Will Likely Cause "Niacin Flush." For Non-Flush, try Niacinamide. Consuming On An Empty Stomach May Increase Flush Reaction
  • 240 Capsules of immediate release Niacin Per Bottle
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in A GMP Compliant, FDA Registered Facility
#4 Real Supplements Rated Best in 2020
Doctor's Best TimeRelease Niacin with Niaxtend NonGMO Vegan Gluten Free 500 mg Tablets, 120 Count
  • Real Niacin provides niacin in an 8-hour extended-release form that enables you to enjoy the health benefits of niacin without experiencing the uncomfortable skin flushing that commonly accompanies other forms of niacin
  • Niacin, also known as vitamin B3 or nicotinic acid, supports more than 500 enzymatic reactions that play pivotal roles in metabolism, energy production, and healthy aging
#5 Real Supplements Rated Best in 2020
Nutricost Niacin (Vitamin B3) 100mg, 240 Capsules - with Flushing, Non-GMO, Gluten Free
  • 100mg of Niacin (Vitamin B3) Per Capsule
  • Warning: Will Likely Cause "Niacin Flush." For Non-Flush, try Niacinamide. Consuming On An Empty Stomach May Increase Flush Reaction
  • 240 Capsules of immediate release Niacin Per Bottle
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in A GMP Compliant, FDA Registered Facility
Sale#6 Real Supplements Rated Best in 2020
NOW Supplements, Niacin (Vitamin B-3) 500 mg, Flush-Free, Double Strength, Nutritional Health, 90 Veg Capsules
  • DOUBLE STRENGTH 500 mg VEGGIE CAPSULES/FLUSH-FREE: Flush-free niacin contains inositol hexanicotinate, a form of niacin that consists of six molecules of niacin linked to a single inositol molecule. It is slowly broken down in the body to yield free niacin and inositol. This gradual release of niacin allows for true niacin activity without the characteristic niacin flush that many people cannot tolerate.
  • NUTRITIONAL HEALTH: Niacin (vitamin B-3) is an essential B-Complex vitamin.
  • CERTIFICATIONS/CLASSIFICATIONS: Vegan/Vegetarian, Made without Gluten, Non-GMO
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968
#7 Real Supplements Rated Best in 2020
Life Extension No Flush Niacin, B3 for heart health, cholesterol & energy support, non-GMO, gluten-free, 100 capsules
  • Flush-free vitamin B supplement—Niacin (a.k.a. B3) supports cardiovascular health and more. But some niacin supplements can cause uncomfortable flushing. This formula contains inositol hexanicotinate to help reduce flushing.
  • Rev up your metabolism—Because vitamin B3 is required for your body to utilize fats and carbohydrates from the foods you eat, niacin also promotes a healthy metabolism...so you can “B” your very best!
  • Get a boost with vitamin B3—Niacin is a water-soluble B vitamin crucial for energy production, particularly to help your body metabolize sugar, fat and alcohol. Niacin also helps promote healthy cellular energy production.
  • Ingredients matter—We use only the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for everyone.
  • Live your healthiest life—We believe the answers to a healthier life are within reach and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
Sale#9 Real Supplements Rated Best in 2020
Life Extension Vitamin B3 Niacin 500 mg – Niacin (Vitamin B3), Supports Heart Health, Promotes cellular energy production – Gluten-Free, Non-GMO – 100 Capsules
  • HEART HEALTHY NIACIN - Niacin, or vitamin B3, was the third B vitamin to be discovered. Niacin has a beneficial effect on your blood lipids. Each gluten-free capsule in our formula delivers 500 mg of this vital nutrient to maintain heart health and more!
  • GET A BOOST WITH VITAMIN B3 – Niacin is a water-soluble B vitamin that is crucial for energy production, particularly to help your body metabolize sugar, fat and alcohol. Niacin also helps promote healthy cellular energy production.
  • REV UP YOUR METABOLISM – Because vitamin B3 is required for your body to utilize fats and carbohydrates from the foods you eat, niacin also promotes a healthy metabolism...so you can “B” your very best!
  • INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. This product is certified non-GMO and gluten-free. Manufactured in the USA and a Certificate of Analysis is available for every product we produce.
  • LIVE YOUR HEALTHIEST LIFE - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach and that rigorous scientific research is the path to get us there. Or formulations are created using the exact ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.
#10 Real Supplements Rated Best in 2020
Rugby Niacin 500 mg 1000 Tabs
  • 500 mg tablets
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • Promotes healthy tissues
  • Maintains a healthy lipid balance
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Sale#11 Real Supplements Rated Best in 2020
Nature's Bounty Flush Free Niacin 500 Mg, 240 Capsules (2 X 120 Count Bottles)
1,114 Reviews
Nature's Bounty Flush Free Niacin 500 Mg, 240 Capsules (2 X 120 Count Bottles)
  • Pack of 240 Capsules (Packed as 2 x 120 count bottles)
  • Supports heart health. Supports carbohdrate and protein metabolism.*
  • Helps maintain healthy skin.*
  • Flush-free formula.**
  • These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. **NOTICE: Most people should not experience flushing when using this product. However, a few sensitive individuals may experience some flushing. Do not take on an empty stomach.
#12 Real Supplements Rated Best in 2020
Kal 50 Mg Niacin Tablets, 200 Count
  • Inside Out Support: Niacin may help support healthy energy metabolism, nerves, GI tract & skin
  • Feel the Flush: Healthy blood flow support; may cause temporary flushing or tingling sensation
  • ActivTab Tech: Tablet disintegration within 30 minutes according to USP standards
  • KAL Quality: Manufactured in our own facility; Vegetarian & Lab Verified for potency & purity
Sale#13 Real Supplements Rated Best in 2020
21st Century Niacin 500 mg Prolonged Release Tablets, 100 Count (27474)
  • Allergen information: mustard_free
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • Compare to active ingredient in slo niacin
  • No added sugar, salt, yeast, preservatives, artificial flavors or colors
  • This product is not intended to diagnose, treat, cure or prevent any disease.
Sale#14 Real Supplements Rated Best in 2020
NOW Supplements, Niacin (Vitamin B-3) 250 mg, Flush-Free, Nutritional Health, 180 Veg Capsules
1,088 Reviews
NOW Supplements, Niacin (Vitamin B-3) 250 mg, Flush-Free, Nutritional Health, 180 Veg Capsules
  • FLUSH-FREE NIACIN 250 mg VEGGIE CAPSULES: Flush-free Niacin contains Inositol Hexanicotinate, a form of Niacin that contains six molecules of niacin linked to a single inositol molecule. It is slowly broken down in the body to yield free niacin and inositol. This gradual release of Niacin allows for true Niacin activity without the characteristic Niacin flush that many people cannot tolerate.
  • NUTRITIONAL HEALTH: Niacin (Vitamin B-3) is an essential B-Complex vitamin.
  • CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian, Made without Gluten
  • GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
  • Packaged in the USA by a family owned and operated company since 1968
#15 Real Supplements Rated Best in 2020
ENDUR-ACIN Niacin - Vitamin B3 Niacin 500mg Extended Release & Low-Flush, 200 Tablets - Supports Cholesterol Balance & Heart Health - Endurance Products
1,931 Reviews
ENDUR-ACIN Niacin - Vitamin B3 Niacin 500mg Extended Release & Low-Flush, 200 Tablets - Supports Cholesterol Balance & Heart Health - Endurance Products
  • LOW-FLUSH NIACIN: Each Endur-Acin tablet contains 500mg of niacin as nicotinic acid (vitamin B-3) in a vegetable wax matrix (tablet core) for an extended release over 6-8 hours.
  • HEART HEALTH AND CHOLESTEROL BALANCE: Backed by clinical research and may help maintain healthy cholesterol levels within the normal range.*
  • OPTIMAL ABSORPTION & MAXIMUM EFFECTIVENESS: The proprietary vegetable-based wax matrix melts at body temperature to slowly release nutrients over 6-8 hours, mimicking how your body processes food. This minimizes side effects and digestive upset.*
  • FREE OF COMMON ALLERGENS: Vegan/Vegetarian safe. No milk, egg, fish, shellfish, tree nuts, peanuts, wheat, corn, yeast, or soy. Gluten-free. No salt, sugar, starch, artificial flavorings, or preservatives.
  • MEETS STRICT GOOD MANUFACTURING PRACTICES: Manufactured and packaged in the Pacific Northwest, USA at an FDA registered facility. Family-owned and operated since 1978.
Sale#16 Real Supplements Rated Best in 2020
Nutricost Niacinamide (Vitamin B3) 500mg, 240 Capsules - Non-GMO, Gluten Free, Flush Free Vitamin B3
15,800 Reviews
Nutricost Niacinamide (Vitamin B3) 500mg, 240 Capsules - Non-GMO, Gluten Free, Flush Free Vitamin B3
  • 240 Capsules of Niacinamide Per bottle
  • 500mg of Vitamin B3 (Niacinamide) Per Capsule
  • Get The Benefits of Vitamin B3 Without The "Niacin Flush"
  • High Quality Vitamin B3 - Niacinamide. May Have White or Blue Lid
  • Non-GMO, Gluten Free, Soy Free, and Made in a GMP Compliant, FDA Registered Facility
Sale#17 Real Supplements Rated Best in 2020
Solgar Niacin (Vitamin B3) 500 mg, 250 Vegetable Capsules - Cardiovascular Support - Energy Metabolism - Non-GMO, Vegan, Gluten Free, Dairy Free, Kosher - 250 Servings
  • Vitamin B3; Niacin (also known as vitamin B3) is a water-soluble vitamin and is part of the B Complex; This formulation provides 500 mg per serving
  • Energy Metabolism; Niacin is required for the metabolism of carbohydrates and protein into energy
  • Cardiovascular Health; Niacin supports cardiovascular health, promotes increased blood flow, and supports the health of the nervous system
  • Non-GMO, Gluten, Wheat & Dairy Free; Solgar Niacin is vegan, kosher, and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for vegetarians
  • The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
#18 Real Supplements Rated Best in 2020
Designs for Health Niacin 500mg - Niacin CRT Vitamin B3 (Nicotinic Acid), Controlled Slow Release Tablets to Help Minimize Flush - Non-GMO, Gluten Free Supplement (60 Tablets)
  • SUPPORT HEALTHY BLOOD LIPIDS - Niacin, also known as vitamin B3 or nicotinic acid, is essential in many metabolic pathways in the body. Niacin's ability to support already healthy blood lipids was discovered in the 1950s. Additionally, it may also be helpful in supporting healthy circulation.*
  • THERAPEUTIC DOSE - Niacin CRT offers therapeutic doses of niacin as nicotinic acid in a controlled-release tablet for optimal bioavailability. It is available in 500 mg and 750 mg tablets.*
  • SLOW RELEASE NIACIN - Niacin CRT has a unique delivery system designed to provide a slow (6-8 hour) continuous release of niacin in a very uniform manner. This helps to eliminate spikes and surges in blood levels of the compound, which often occur with immediate-release delivery systems.*
  • HIGHER STANDARDS. BETTER RESULTS - Designs for Health maintains a strict, no-compromises approach to quality raw material selection. We never cut corners with substandard ingredients. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly.
  • OVER 50,000 DOCTORS AGREE - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.
#19 Real Supplements Rated Best in 2020
THORNE Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep - Gluten-Free - 180 Capsules
1,375 Reviews
THORNE Niacinamide - 500mg Niacin - Non-Flushing Form of Vitamin B3 - Support Joint Health, Skin Health & Restful Sleep - Gluten-Free - 180 Capsules
  • Vitamin B3: A non-flushing form of vitamin B3
  • Sleep: Supports restful sleep*
  • Joints: Supports joint health*
  • Free From: Every Thorne product is made with the purest possible ingredients - without gluten or other major allergens (eggs, tree nuts, peanuts) This product also contains no soy, dairy, shellfish, or fish
  • Thorne's commitment to integrity and science-backed products has helped us earn the trust of thousands of health-care professionals, U.S. National Teams, the Mayo Clinic, and families around the world
#20 Real Supplements Rated Best in 2020
Swanson Niacin (Vitamin B3) - Vitamin Supplement Supporting Heart Health and Carbohydrate Metabolism - Promotes Natural Energy Production - (250 Tablets, 100mg NE Each)
  • PROMOTES HEART HEALTH: Swanson's premium niacin supplement contains B-vitamin nutrition to promote cardiovascular health by supporting healthy lipid levels. Our vitamin B3 supplement is a safe, natural way to take care of your heart!
  • NATURAL ENERGY SUPPORT: These niacin capsules support carbohydrate metabolism, helping to supply the whole body with energy needed for everyday physical function. Our supplement delivers 100mg NE per capsule.
  • DOSAGE INSTRUCTIONS: Our wellness supplements offer everyday solutions for an enhanced mind, body, and home using only the purest ingredients. For best results, take one capsule per day with food and water.
  • OUR QUALITY COMMITMENT: For nearly 50 years, Swanson has delivered science-backed health products worldwide. Each wellness supplement is made in our GMP certified facilities, and our purity and potency testing includes independent third-party labs.
  • MONEY BACK GUARANTEE: At Swanson, we guarantee that every health product is made from the purest, freshest nutrients. If you aren't satisfied with any product(s) purchased within the last 30 days, return the unused portion to us for a full refund.

Best 10 Benefits of Niacin

Vitamin B3, also known as niacin, is an essential nutrient required for everyday function. Deficiency in this vitamin can lead to skin problems, memory loss, and even hallucinations or cognitive impairment. On a more positive note, here are ten benefits of regular niacin consumption:

1. Maintains lipid levels

The body needs a healthy balance of lipids, including cholesterol and triglycerides. Niacin promotes low levels of LDL cholesterol and higher levels of HDL cholesterol, and prevents the body from holding on to too many triglycerides.

2. Promotes healthy skin

Is your skin damaged by acne scars or rosacea? Niacin may be able to help. Proper intake nourishes the skin and can reverse damage caused by severe acne and other skin problems, and has even been shown to reduce the risk of skin cancer.

3. Prevents cognitive impairments

Niacin is known for its antidepressant properties and ability to promote brain repair. Aging adults may find niacin beneficial in preventing dementia, Alzheimer’s, schizophrenia, and other cognitive disorders associated with old age.

4. Treats diabetes

This vitamin helps maintain a healthy blood sugar level. Niacin is also useful in preventing diabetes-related conditions such as heart disease.

5. Prevents pellagra

Pellagra is a serious result of niacin deficiency and can only be treated with high doses of the B complexes, the most useful of which is nicotinamide.

6. Relieves arthritis

Niacinamide has been found to reduce join pain and inflammation in patients with osteoarthritis; additionally, it is known to promote muscle growth.

7. Prevents birth defects

Nicotinamide adenine dinucleotide (NAD) is responsible for DNA synthesis. Research has suggested that regular niacin intake by pregnant women ensures the proper function of NAD and prevents maldevelopment and birth defects in unborn children.

8. Treats erectile dysfunction

Niacin acts as a vasodilator, allowing blood flow to the genitals during intercourse, thereby allowing men to achieve and maintain an erection.

9. Relieves motion sickness

Niacin, particularly when taken from papayas, has been shown to be instrumental in reducing motion sickness.

10. Aids in digestion

Vitamin B3 aids in the digestion of fats and carbohydrates; a deficiency can lead to stomachaches, constipation, and other indigestion disorders.


Real Supplements gives you the best Niacin on the market today. Our top-rated lists are fresh and current so you get the best options.

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