Best Pyridoxine

#1 Real Supplements Rated Best in 2020
EZ Melts B6 as Pyridoxine, 50 mg, Sublingual Vitamins, Vegan, Zero Sugar, Natural Orange Flavor, 60 Fast Dissolve Tablets
  • ESSENTIAL VITAMIN B6 - EZ Melts B6 is key for supporting central nervous system function and cardiovascular health. B6 is essential for protein, fat and carbohydrate metabolism as well as the creation of red blood cells and neurotransmitters.
  • PROMOTES A HEALTHY HEART - Vitamin B6 may prevent clogged arteries and minimize heart disease risk, by helping to reduce high homocysteine levels that lead to narrowing of arteries, which is great for the longevity of your health.
  • GREAT TASTING, FAST MELT TABLETS - Natural orange flavor combined with our fast-melting technology produces a pleasant, easy to take tablet that melts in your mouth. Many other b6 supplements are hard to swallow with an awful taste and scent.
  • MOOD REGULATION - B6 is necessary for creating neurotransmitters that regulate emotions and maintaining healthy homocysteine levels. Several studies have shown that depressive symptoms are associated with low blood levels and intakes of vitamin B6.
  • MADE IN THE USA AND QUALITY TESTED - All EZ Melts vitamins are manufactured in sunny Florida with domestic and globally sourced ingredients. Every ingredient is tested by independent 3rd Party Labs located in the USA, ensuring purity and safety.
#2 Real Supplements Rated Best in 2020
Nutricost Vitamin B6 (Pyridoxine HCl) 100mg, 240 Capsules
  • 100mg of Vitamin B6 (Pyridoxine HCl) per Capsule
  • 240 Vitamin B6 Capsules In Each Bottle
  • 1 Serving, Just 1 Capsule
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility
Sale#3 Real Supplements Rated Best in 2020
NOW Supplements, Vitamin B-6 (Pyridoxine HCl) 100 mg, Cardiovascular Health*, 250 Capsules
2,975 Reviews
NOW Supplements, Vitamin B-6 (Pyridoxine HCl) 100 mg, Cardiovascular Health*, 250 Capsules
  • Supports Healthy Homocysteine Metabolism*
  • Important for Nervous System Function*
  • Cardiovascular Health*
  • GMP Quality Assured: NOW closely adheres to both mandatory U.S. FDA Current Good Manufacturing Practices (CGMP) regulations and voluntary Natural Products Association (NPA) Good Manufacturing Practices (GMP) regulations. Good manufacturing practices ensure compliance with sanitation, processing, documentation, and testing requirements that are designed to promote consistent, highly reproducible product quality and safety.
  • Packaged in the USA by a family owned and operated company since 1968
#4 Real Supplements Rated Best in 2020
Thorne Research - Pyridoxal 5'-Phosphate - Bioactive Vitamin B6 (Pyridoxine) Supplement for Energy Production and Neurotransmitter Synthesis - 180 Capsules
103 Reviews
Thorne Research - Pyridoxal 5'-Phosphate - Bioactive Vitamin B6 (Pyridoxine) Supplement for Energy Production and Neurotransmitter Synthesis - 180 Capsules
  • Active B6: The active form of vitamin B6 that is readily used by the body
  • Multiple Functions: An essential cofactor for the synthesis of amino acids and numerous neurotransmitters (brain chemicals)*
  • PMS: Pairs with magnesium for support of women with PMS*
  • Free From: Every Thorne product is made with the purest possible ingredients - without gluten or other major allergens (eggs, tree nuts, peanuts). This product also contains no soy, dairy, yeast, shellfish, or fish.
  • Thorne's commitment to integrity and science-backed products has helped us earn the trust of thousands of health-care professionals, U.S. National Teams, the Mayo Clinic, and families around the world.
#5 Real Supplements Rated Best in 2020
Vitamin B6 (Pyridoxine) Drops – Liquid Vitamin B Drops for Natural Brain Function Support, Blood Vessels & Immune Support – Liquid Vitamin Mood Supplement – Alcohol-Free Health Supplement (1 Fl Oz)
48 Reviews
Vitamin B6 (Pyridoxine) Drops – Liquid Vitamin B Drops for Natural Brain Function Support, Blood Vessels & Immune Support – Liquid Vitamin Mood Supplement – Alcohol-Free Health Supplement (1 Fl Oz)
  • BOOST ENERGY AND CONCENTRATION: These liquid Vitamin B drops can offer brain health and mood support, converting carbs, fats and proteins into rich energy to improve focus and reduce fatigue.
  • IMPROVE EYES & SKIN HEALTH: Along with a healthy diet, Vitamin B drops can help maintain good eye health along with improving blood vessels and radiant, glowing skin tones and complexion.
  • IMMUNE SUPPORT: This B Vitamin can help with immune system support along with maintaining a great nervous system health, and promoting hormone production to promote emotional and mental health.
  • PURE, POTENT & MADE IN THE USA: HoneyCombs Industries liquid B supplements are manufactured in the USA with zero fillers, artificial preservatives, colors or flavors and no gluten, soy, milk or egg.
  • FEEL BETTER OR YOUR MONEY BACK: We guarantee that you’ll love our Vitamin B sublingual drops or you can ship it back to us within 30 days of ordering for a full refund, no questions asked.
#6 Real Supplements Rated Best in 2020
Allergy Research Group - Pyridoxine P5P - High Dose Vitamin B6, Pyridoxal-5-Phosphate - 60 Vegetarian Capsules
29 Reviews
Allergy Research Group - Pyridoxine P5P - High Dose Vitamin B6, Pyridoxal-5-Phosphate - 60 Vegetarian Capsules
  • High dose pyridoxine HCl and pyridoxal-5-phosphate (P-5-P), the "activated" form of vitamin B6*
  • Plays an important role in homocysteine metabolism and production of some neurotransmitters*
  • Suggested Use: Take 1 capsule daily with a meal, or as directed by a healthcare practitioner
  • Free of wheat and gluten, dairy, eggs, soy, fish, shellfish, peanuts, tree nuts, corn, and yeast
  • Since 1979 Allergy Research Group has committed to using pure and low allergy potential ingredients
#7 Real Supplements Rated Best in 2020
Klaire Labs Vitamin B6 - 250 Milligrams Hypoallergenic High Potency Pyridoxine HCl for Immune & Nervous System Support, Assists B12 Absorption (150 Vegetarian Capsules)
48 Reviews
Klaire Labs Vitamin B6 - 250 Milligrams Hypoallergenic High Potency Pyridoxine HCl for Immune & Nervous System Support, Assists B12 Absorption (150 Vegetarian Capsules)
  • High-potency pyridoxine HCl.
  • Supplies 250 mg of Vitamin B6 as pyridoxine HCl per vegetarian capsule.
  • Vitamin B6 assists protein and fat metabolism, red blood cell production, immune and nervous system function, nucleic acid synthesis, enzyme activation, and B12 absorption.*
  • Hypoallergenic* product free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, corn, and yeast. Contains no artificial colors, flavors or preservatives.
  • Trusted by healthcare practitioners since 1969, Klaire Labs products are developed closely with physicians and are intended to be used as directed by a healthcare practitioner.
#8 Real Supplements Rated Best in 2020
BulkSupplements.com Vitamin B6 50mg (Pyridoxine HCl) Powder - Memory Vitamins for Men - Nerve Support Formula - B6 Vitamins (100 Grams - 3.5 oz)
280 Reviews
BulkSupplements.com Vitamin B6 50mg (Pyridoxine HCl) Powder - Memory Vitamins for Men - Nerve Support Formula - B6 Vitamins (100 Grams - 3.5 oz)
  • MOOD SUPPORT - Pyridoxine HCl may support healthy mood, promote a positive outlook, and help reduce apprehension.*
  • HEART HEALTH - The body uses vitamin B6 to make amino acids that are used in the production of red blood cells.* Vitamin B6 also helps convert homocysteine into another amino acid called methionine which is then converted into glutathione, an antioxidant that supports heart health.*
  • JOINT HEALTH - Vitamin B6 contributes to bone metabolism and collagen formation which can help maintain healthy joints.* It also may contribute to cartilage formation and maintenance of normal bones and teeth.*
  • SLEEP AID - Pyridoxine HCl may support healthy sleep patterns by promoting relaxation before bedtime. It may also support energy levels during the day by helping you fall asleep faster at night.*
#9 Real Supplements Rated Best in 2020
NaturesPlus Vitamin B6 (Pyridoxine HCI), Sustained Release - 500 mg, 90 Vegetarian Tablets - Energy & Metabolism Booster, Memory, Mood, Immune Support Supplement - Gluten-Free - 90 Servings
266 Reviews
NaturesPlus Vitamin B6 (Pyridoxine HCI), Sustained Release - 500 mg, 90 Vegetarian Tablets - Energy & Metabolism Booster, Memory, Mood, Immune Support Supplement - Gluten-Free - 90 Servings
  • VITAMIN B6: Known for its versatility, Vitamin B6 plays a role in enzyme reactions, in proper brain function and cognitive development, in converting food into cellular energy, and in the making of serotonin hormone that regulates mood.
  • POTENCY: We loaded 500 mg of Vitamin B6 to each tablet supplying you a high-potency daily dietary supplement. The Sustained Release Tablets provide a gradual release of ingredients over a prolonged period of time.
  • PURITY: Our Vitamin B6 supplement is hypoallergenic, gluten free, vegetarian, and it is free from artificial colors and preservatives, and from the common allergens yeast, wheat, corn, soy and milk.
  • QUALITY MANUFACTURING: Our state-of-the-art manufacturing facilities maintain continuous adherence to cGMP compliance, superior standards, and are FDA and NSF registered.
  • SERVING: 90 tablets provide 90 servings.
#11 Real Supplements Rated Best in 2020
Swanson Vitamin B-6 (Pyridoxine) Cardio Health Support Energy Metabolism 100 Milligrams 250 Capsules
  • An economical source for cardio health and energy metabolism
  • Supports the normal breakdown of fats, proteins and more
  • Each serving delivers 100 mg of vitamin B6
  • Per GMP guidelines set forth by the FDA, most products are formulated for 24 months from the date of manufacture. Liquids and probiotics are formulated for 12 months.
  • OUR QUALITY & HERITAGE COMMITMENT - We're control freak...in a good way! For nearly 50 years, Swanson Health has delivered science-backed health and wellness products to people around the world. In 1969 in Fargo, ND, Swanson began with a mission to offer pure and potent health and wellness solutions that help people live simply healthier together. Our facilities areGood Manufacturing Practices (GMP) certified, and we voluntarily participate in third-party, independent laboratory testing.
#12 Real Supplements Rated Best in 2020
Beelith Tablets Magnesium Supplement with and pyridoxine HCL - 100 Each
65 Reviews
Beelith Tablets Magnesium Supplement with and pyridoxine HCL - 100 Each
  • Beelith Tablets With Magnesium And Pyridoxine HCL As a dietary supplement for patients with magnesium.
  • Vitamin B 6 deficiencies resulting from malnutrition, alcoholism, magnesium depleting drugs.
  • Dietary supplement with magnesium, Vitamin B6 deficiencies.
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
#13 Real Supplements Rated Best in 2020
Best Vitamin B6 - 100mg Pyridoxine Vitamin B-6 Tablet - Support Cardiovascular Health, Healthy Immune System, Brain & Nerve Function
  • ✔️ PURE & POTENT VITAMIN B-6 - Highly Bioavailable Form Of Natural Vitamin B-6, Pyridoxine, Provides Superior Absorption And A Wide Range Of Benefits.
  • ✔️ SELECTIVELY SOURCED - Using The Best Lab-Tested Ingredients - 100% Gluten Free, Soy Free, With NO Fillers, Artificial Preservatives, Colors, or Flavors. Made In FDA Registered, GMP-Certified USA Facilities.
  • ✔️ SUPERIOR HEALTH BENEFITS YOU CAN FEEL - Vitamin B-6 Supplements Play A Vital Role In Metabolic Nutrition By Helping Break Down Carbohydrates, Proteins, And Fats To Provide More Energy From The Food You Eat.
  • ✔️ BEST-IN-CLASS FORMULA - Provides An All Natural Form Of Vitamin B-6 That Is Superior To Other Supplements and Delivers Benefits That Include Improved Metabolic Function, Healthy Nervous System, Cardiovascular Health, Blood Sugar Balance & More.
  • ✔️ QUALITY AND POTENCY GUARANTEED - Best Vitamin B Complex B-6 Supplement - Made Under Strict Quality Control Standards, Using Lab Tested Ingredients To Ensure Maximum Potency And Quality, GUARANTEED.
#14 Real Supplements Rated Best in 2020
NaturesPlus Vitamin B6 (Pyridoxine HCI), Sustained Release - 500 mg, 90 Vegetarian Tablets - Energy Support Supplement, Mood Booster - Gluten-Free - 90 Servings
55 Reviews
NaturesPlus Vitamin B6 (Pyridoxine HCI), Sustained Release - 500 mg, 90 Vegetarian Tablets - Energy Support Supplement, Mood Booster - Gluten-Free - 90 Servings
  • ENERGY METABOLISM SUPPORT - Vitamin B6 is part of the B Complex Vitamins that are essential to the metabolism of fat, carbohydrates, and protein. It is important to energy production
  • HEALTHY BRAIN FUNCTION - Vitamin B6 plays a role in mood regulation, as it helps regulate neurotransmitters tied to emotions
  • CARDIOVASCULAR AND HEART HEALTH - B6 plays an integral role in the production of red blood cells (hemoglobin).
  • OTHER BENEFITS - Vitamin B6 has also been used to help with the emotional symptoms.
  • QUALITY MANUFACTURING: Our state-of-the-art manufacturing facilities maintain continuous adherence to cGMP compliance, superior standards, and are FDA and NSF registered
#15 Real Supplements Rated Best in 2020
Spring Valley - Vitamin B-6 (Pyridoxine) 100 mg, 250 Tablets
1,216 Reviews
#16 Real Supplements Rated Best in 2020
NaturesPlus Vitamin B6 (Pyridoxine HCI) - 100 mg, 90 Vegetarian Tablets - Energy & Metabolism Booster, Hair Skin & Nails, Memory, Mood, Immune System Support Supplement - Gluten-Free - 90 Servings
2 Reviews
NaturesPlus Vitamin B6 (Pyridoxine HCI) - 100 mg, 90 Vegetarian Tablets - Energy & Metabolism Booster, Hair Skin & Nails, Memory, Mood, Immune System Support Supplement - Gluten-Free - 90 Servings
  • VITAMIN B6: Known for its versatility, Vitamin B6 plays a role in enzyme reactions, in proper brain function and cognitive development, in converting food into cellular energy, and in the making of serotonin hormone that regulates mood.
  • POTENCY: We loaded 500 mg of Vitamin B6 to each tablet supplying you a high-potency daily dietary supplement. The Sustained Release Tablets provide a gradual release of ingredients over a prolonged period of time.
  • PURITY: Our Vitamin B6 supplement is hypoallergenic, gluten free, vegetarian, and it is free from artificial colors and preservatives, and from the common allergens yeast, wheat, corn, soy and milk.
  • QUALITY MANUFACTURING: Our state-of-the-art manufacturing facilities maintain continuous adherence to cGMP compliance, superior standards, and are FDA and NSF registered.
  • SERVING: 90 tablets provide 90 servings.
#17 Real Supplements Rated Best in 2020
Best Naturals Vitamin B-6 25 Mg Tablets, 250 Count
  • Supports Healthy Cardiovascular System
  • Supports Healthy Homocysteine Level
  • Supports Nervous System Function
  • During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
Sale#18 Real Supplements Rated Best in 2020
Solgar Vitamin B6 25 mg, 100 Tablets - Supports Energy Metabolism, Heart Health & Healthy Nervous System - B Complex Supplement - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings
829 Reviews
Solgar Vitamin B6 25 mg, 100 Tablets - Supports Energy Metabolism, Heart Health & Healthy Nervous System - B Complex Supplement - Vegan, Gluten Free, Dairy Free, Kosher - 100 Servings
  • B Complex Supplement; Vitamin B6 is part of the group of essential nutrients known as the B Complex; This formulation provides 25mg of vitamin B6 per serving
  • Energy Metabolism; B Complex vitamins, including B6, work to support energy metabolism in the body; B6 helps maintain a healthy nervous system
  • Heart Health; Along with folic acid and B12, B6 promotes heart health by supporting healthy levels of homocysteine already in a normal range; It also plays an integral role in the production of red blood cells
  • Gluten, Wheat & Dairy Free; Solgar Vitamin B6 is suitable for vegans and free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives, and color; Suitable for vegetarians
  • The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
Sale#19 Real Supplements Rated Best in 2020
Nature's Way Vitamin B-6, 50 mg per serving
1,747 Reviews
Nature's Way Vitamin B-6, 50 mg per serving
  • For cellular energy support.*
  • Vitamin B6 is converted into the main enzyme responsible for amino acid and protein metabolism.*
  • Carefully tested and produced to superior quality standards.
  • Gluten-free. No salt, yeast-derived ingredients, wheat, soy, corn, dairy, or artificial colors, flavors, or preservatives.
  • Bottle made with 97% post-consumer recycled materials. Please recycle.
#20 Real Supplements Rated Best in 2020
Beelith Tablet 3 Pack (Magnesium Supplement with and Pyridoxine Hcl) - 3 X 100 Tab
13 Reviews

Best 10 Benefits of Pyridoxine

Vitamin B6 has numerous derivatives: pyridoxal, pyridoxal 5-phosphate, pyridoxine, pyridoxine 5-phosphate, pyridoxamine, and pyridoxamine 5-phosphate. The average adult needs just about 1.3 mg daily, an amount that can usually be found sufficiently through a healthy diet. Foods rich in vitamin B6 include turkey, salmon, chicken, tuna, pistachios, walnuts, and eggs. Let’s look at ten amazing health benefits of this B complex vitamin.

1. Nourishes skin

Healthy levels of vitamin B6 promote increased production of collagen, a substance necessary for young, flawless skin. Decreased levels of collagen lead to wrinkles, spots, and more. This vitamin also helps clear up other skin issues, including acne, eczema, dry skin, and dandruff.

2. Prevents cardiovascular disease

Studies show that regular intake of vitamin B6 leads to a reduced risk of coronary heart disease, heart failure, and stroke. This vitamin controls the level of homocysteine, which is related to inflammation and heart attack.

3. Strengthens the nervous system

Research suggests that this same compound, homocysteine, can cause brain damage and cognitive malfunctions such as epilepsy when present in high amounts. Regular intake of vitamin B6 prevents homocysteine levels from becoming too high, thus promoting a healthy central nervous system.

4. Treats anemia

A vitamin B6 deficiency can lead to anemia. Recent studies show that vitamin B6 supplements produce the hemoglobin necessary to treat and prevent anemia. This hemoglobin ensures that iron is properly utilized and oxygen is transported to all cells.

5. Improves mood

Clinical studies have shown that vitamin B6 supplements increase the level of serotonin—the happiness hormone—and boosts energy.

6. Promotes regular sleep

A vitamin B6 deficiency leads to overproduction of kynurenine, a compound that causes low levels of melatonin and serotonin, thus leading to insomnia and other sleep problems. Sufficient vitamin B6, however, allows the body to fall asleep quickly and maintain a regular sleep cycle.

7. Prevents vision loss

Research has shown that daily intake of vitamin B6 slows down macular degeneration, particularly in old age, and prevents other forms of vision loss and eye conditions.

8. Fights diabetes

Increased consumption of vitamin B6 has been linked to diabetes prevention, both regular forms as well as gestational diabetes. This vitamin also improves glucose tolerance, which can relieve some symptoms of diabetes.

9. Alleviates anxiety and depression

A low level of vitamin B6 deficiency is strongly correlated with symptoms of depression and panic attacks. By increasing serotonin levels, this vitamin prevents and alleviates symptoms of serious depressive disorders.

10. Treats asthma

Some studies suggest that vitamin B6 is effective in preventing asthma attacks. Asthma attacks occur when bronchial tubes tighten, but vitamin B6 is capable of relaxing these muscles and preventing wheezing.


Real Supplements gives you the best Vitamin B6 on the market today. Our top-rated lists are fresh and current so you get the best options.

Amazon Best Rated Products - Last Updated on 2021-09-21.

DISCLAIMER: There are affiliate links on this page. This means that at no cost to you, we will receive a small commission if you purchase through our link.