Sustamine® is a dipeptide consisting of two amino acids (L-alanine and L-glutamine) connected by a peptide bond. Sustamine is stable in both heat and acids, is highly soluble, and can function as a source of glutamine in the body.


Top Sustamine

SaleBest Seller No. 1
Atrantil (90 Clear Caps): Bloating, Abdominal Discomfort, Change in Bowel Habits, and Everyday Digestive Health
  • Do YOU BLOAT AFTER EATING CERTAIN FOODS? If yes, then you should try Atrantil
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SaleBest Seller No. 2
ANDROSURGE Estrogen Blocker for Men - Natural Anti-Estrogen, Testosterone Booster & Aromatase Inhibitor Supplement - Boost Muscle Growth & Fat Loss - DIM & 6 More Powerful Ingredients, 60 Veggie Pills
1,031 Reviews
ANDROSURGE Estrogen Blocker for Men - Natural Anti-Estrogen, Testosterone Booster & Aromatase Inhibitor Supplement - Boost Muscle Growth & Fat Loss - DIM & 6 More Powerful Ingredients, 60 Veggie Pills
  • ELITE ESTROGEN BLOCKER FOR MEN. Androsurge is the first scientifically-dosed, non-proprietary blend, all-natural estrogen reducing supplement for men. Featuring research-supported ingredients such as grape seed extract and diindolylmethane (DIM).
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SaleBest Seller No. 3
Extra Strength L Arginine - 1200mg Nitric Oxide Supplement for Muscle Growth, Vascularity & Energy - Powerful NO Booster With L-Citrulline & Essential Amino Acids To Train Longer & Harder
2,272 Reviews
Extra Strength L Arginine - 1200mg Nitric Oxide Supplement for Muscle Growth, Vascularity & Energy - Powerful NO Booster With L-Citrulline & Essential Amino Acids To Train Longer & Harder
  • SUPERIOR EXTRA STRENGTH L ARGININE - Our Premium L Arginine stacks Arginine HCI & Arginine Alpha Ketoglutrate with Citrulline, a precursor to Nitric Oxide (NO) production. We have combined the two best NO forms with Citrulline to provide the ultimate, synergistic blend of the three key Nitric Oxide ingredients to ensure you are getting ALL that Arginine can offer!
  • SAFELY SUPPORTS HEALTHY LIFESTYLE & LEAN MUSCLE - L Arginine is an essential amino acid that converts into Nitric Oxide, thereby helping to promote healthy circulation.* Often used as a sports nutrition supplement, NO supplementation will help promote blood flow, which means more oxygen reaches your muscle, brain, heart, lungs, & other organs. MORE blood flow to your muscle means more muscle gains and vascularity, leaving you looking your best.
  • SUPPORTS BIGGER PUMPS, PERFORMANCE, VASCULARITY AND GAINS - Arginine supports energy levels and lean muscle.* In addition to promoting blood flow, Arginine is also well known for energy production - perfect for weightlifters, athletes, runners and everyday active people.*
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Best Seller No. 4
Optimum Nutrition L-Glutamine Muscle Recovery Capsules, 1000mg, 120 Count
979 Reviews
Optimum Nutrition L-Glutamine Muscle Recovery Capsules, 1000mg, 120 Count
  • Dietary supplement
  • 1000 mg of pure L-glutamine per capsule
SaleBest Seller No. 5
Electrolyte Concentrate for Rapid Rehydration | NO Calories NO Sugar | 48 Servings | Magnesium, Potassium, Sodium & Zinc | 100% Guaranteed
538 Reviews
Electrolyte Concentrate for Rapid Rehydration | NO Calories NO Sugar | 48 Servings | Magnesium, Potassium, Sodium & Zinc | 100% Guaranteed
  • What is Hi-Lyte? Hi-Lyte is a liquid electrolyte concentrate that can be added to water, juice or any other beverage. It replaces electrolytes lost due to sweat, exercise or even alcohol consumption. Perfect to add to water bottles, camelbaks or hydration packs, as it will not leave a residue or contribute to the growth of mold or bacteria.
  • What are Hi-Lytes benefits? Hi-Lyte's proprietary formulation includes the perfect mix of electrolytes for rapid rehydration and alkalinity*. Support mechanisms include: Reduces heat stress, cramping, nausea and fatigue. Improves energy, muscle recovery, muscle gain and endurance. Antioxidants support healthy immune system function*.
  • Why is Hi-Lyte better? Hi-Lyte is the highest Potassium, Zinc and Magnesium Electrolyte Concentrate available and perfectly balanced for hydration, recovery and alkalinity. It is made of all-natural Sea Minerals including Sea Salt from the Great Salt Lakes in Utah. No Calories. No Sugar. No artifical colors or flavors. Vegetarian. Vegan. Non-GMO. Gluten Free. Keto Diet Approved. Made in the USA in an NSF Certified Manufactring Facility.
  • IMPORTANT: Hi-Lyte IS A HEALTH FOCUSED PRODUCT AND NOT FOCUSED ON TASTE. IT HAS A SLIGHTLY SALTY AND TART TASTE IN WATER. If you're sensitive to the mineral flavor, we recommend adding a squeeze of lemon. Hi-Lyte is made for people who prefer clean food with no additives. It was designed for the demanding needs of endurance athletes such as Cyclists, Runners, Swimmers and Triathletes. Also a favorite of Cross-fitters, Yogi's and Collegiate and Professional athletes of all sports.
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Best Seller No. 6
Ultimate Monolaurin - 21 oz - 186 Servings, 3000 mg Each
  • Approximately 186 servings of 3000 mg each, in easy-to-take pellets.
  • 1 teaspoon = 3000 mg = several capsules' worth!
  • Lowest cost per mg serving.
  • Added "MonoCaprin Plus" support for your immune system.
Best Seller No. 7
IntestinePro Intestine Support for Humans with Non-GMO Wormwood, Black Walnut, Echinacea + 15 More Premium Ingredients, 60 Vegetarian Capsules
  • #1 INTESTINE SUPPORT SUPPLEMENT - The formula you loved is finally back! Thousands of customers agree that our intestine dietary supplement is the most effective one. Teraputics is known as THE leading brand of intestine complex formulas. This is because the only thing we care about is the quality and potency of our ingredients. Many of our customers have great things to say!
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  • MAXIMUM STRENGTH BUT GENTLE ON YOU - 1 capsule of IntestinePro must be taken with meals 3 times daily. For a more intensive dose, you may take 2 capsules with meals 3 times daily. After the bottle is finished and you want to try the product again, we ask that you wait 2 weeks before doing so. Customers that followed these instructions experienced the most effective results.
  • ONLY THE BEST FROM TERAPUTICS - All of our ingredients are perfectly formulated in FDA-registered, GMP compliant facilities, subjected to stringent third party purity testing, and made right here in the USA. Our IntestinePro formula is of the highest quality making it a preferred alternative to other products that carry undesired side effects.
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SaleBest Seller No. 8
Doctor's Best Benfotiamine, Non-GMO, Vegan, Gluten free, Soy Free, Helps Maintain Blood Sugar Levels, 300 mg, 60 Veggie Caps
333 Reviews
Doctor's Best Benfotiamine, Non-GMO, Vegan, Gluten free, Soy Free, Helps Maintain Blood Sugar Levels, 300 mg, 60 Veggie Caps
  • Belonging to the family of compounds knows as allithiamines
  • Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin
  • Helps maintain healthy cells in the presence of blood glucose
  • Vegan
  • Label images may vary
SaleBest Seller No. 9
ZymaDerm for Molluscum, Natural, Fast, Gentle, Painless - FDA Registered, Made in USA, 13 milliliter
  • Natural plant-based anti-viral essential oils quickly eliminate molluscum papules to restore clear skin.
  • Parents apply ZymaDerm with glass applicator. no sting, no hurt. a bottle treats 60 papules, 2x a day for a month.
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  • 86% of doctors surveyed rated it effective. 1 million parents have trusted ZymaDerm to eliminate molluscum.
  • Made in USA in an FDA registered and inspected facility. ZymaDerm FDA number NDC# 69163-4131-1.
Best Seller No. 10
Nutratech Orlistol - Carb and Fat Blocker Weight Loss Aid and Diet Pill for Powerful Fat Burning and Appetite Suppression. Excellent for Keto Diet to Get Back into Ketosis Quickly. 60 Count.
  • Orlistol's proprietary diet pill formula is the only weight loss supplement available that inhibits both the absorption of carbs and fats, allowing them to be passed through the body before they can be broken down and stored for energy (as fat) resulting in fast weight loss for women and men.
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  • High quality and made in the USA. Our products are designed and manufactured in a state of the art facility in the USA. Our products are made to the highest standards of FDA mandated Good Manufacturing Practices ("GMP") and we only source ingredients from FDA approved suppliers.
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Best Seller No. 11
Huperzine A 200mcg (Third Party Tested) Made in The USA, 120 Tablets, Nootropics Brain Supplement to Boost Acetylcholine, Improve Memory and Focus by Double Wood Supplements
  • MADE IN THE USA AND THIRD PARTY TESTED FOR PURITY - Our Huperzine A tablets are manufactured right here in the USA. Third party testing is available upon request.
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  • INCREASE LEVELS OF ACETYLCHOLINE - Huperzine-A acts an acetylcholinesterase inhibitor meaning it increases levels of acetylcholine in the brain.
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  • FOCUS FOR LONGER PERIODS OF TIME - By preventing the brain from breaking down acetylcholine you will be able to stay focused on individual tasks more easily
Best Seller No. 12
RediMind - Natural Cognitive Enhancement Supplement - Non-GMO, Vegan, Gluten-Free
  • CLINICALLY PROVEN. In a clinical study conducted by Princeton Consumer Research, participants scored 51% higher on the ISLT short-term memory test after taking RediMind for only 30 days.
  • TESTED AGAINST PLACEBO. RediMind significantly outperformed placebo, as study participants taking placebo for 30 days scored only 8% higher on the same ISLT short-term memory tests.
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  • 30 DAY MONEY BACK GUARANTEE. No questions asked!
  • Non-GMO Vegan Gluten-Free 30 Veggie Capsules
SaleBest Seller No. 13
Jarrow Formulas BroccoMax, Supports Liver Health, 60 Delayed Veggie Caps
  • Associated with antioxidant and cellular protection
  • Contains a standardized concentration of sulforaphane glucosinolate extracted (without solvents) from broccoli seeds
  • Sulforaphane glucosinolate is metabolized to sulforaphane
  • Keep out of the reach of children
SaleBest Seller No. 14
Goliath by Dr. Emil BCAA Plus with L Glutamine - Branch Chain Amino Acids w/Optimal 2:1:1 Ratio – Enhanced Post Workout Recovery & Growth Stack
40 Reviews
Goliath by Dr. Emil BCAA Plus with L Glutamine - Branch Chain Amino Acids w/Optimal 2:1:1 Ratio – Enhanced Post Workout Recovery & Growth Stack
  • GLUTAMINE ENHANCED BCAA - Our BCAA is enhanced with a high dose of L-Glutamine, which has been shown to enhance BCAA metabolism, creating the ideal synergy for a superior recovery & growth stack.
  • OPTIMAL 2:1:1 BCAA RATIO - Our formula uses an optimal 2:1:1 ratio of L- Leucine, L-Isoleucine & L-Valine for premium muscle growth support & prevention of muscle breakdown, exercise fatigue & soreness.
  • DOCTOR-DRIVEN, SCIENCE BACKED - Bringing Dr. Emil's unique knowledge as both a medical doctor & recognized nutrition expert (he's also a professional bodybuilder!), our blends are painstakingly formulated to provide superior results and are always backed by science - free of gimmicks, fads & false promises.
  • SYNERGISTIC POST-WORKOUT BLEND - On its own, L-Glutamine HAS been clinically shown to support muscle recovery & growth while preventing muscle wasting & breakdown. When combined with the BCAA's it has been indicated to significantly support the metabolism of these vital amino acids, creating a powerful synergistic effect for optimal post-workout recovery.
  • ONLY THE RIGHT STUFF - All Dr. Emil products are made from all-natural vitamins, minerals & herbal extracts, without the use of harmful additives; non-GMO; free of hormones, gluten and all top 8 allergens. All products are manufactured in the USA in an FDA-registered, GMP certified laboratory.
SaleBest Seller No. 15
Dihydromyricetin (DHM) 50 Capsules, 300mg (Third Party Tested) Made in the USA by Double Wood Supplements (DHM Depot)
90 Reviews
Dihydromyricetin (DHM) 50 Capsules, 300mg (Third Party Tested) Made in the USA by Double Wood Supplements (DHM Depot)
  • MADE IN THE USA AND 3RD PARTY TESTED - Our Dihydromyricetin is manufactured and tested right here in the USA (New York). It is also third party tested for purity by Health Level One.
  • 100% MONEY BACK GUARANTEE - We understand supplements don't work the same for everyone and offer a no questions asked 100% money back guarantee. We don't want a single customer to feel ripped off or upset.
  • PREVENT HANGOVERS - When taken after your last drink, before going to bed, DHM helps minimize the effect alcohol has on the body leaving you with less of a hangover the next morning.
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Best Seller No. 16
BodyHealth PerfectAmino (300 Tablets) 8 Essential Amino Acids Supplements with BCAA, Increase Muscle Recovery, Boost Energy & Stamina, 99% Utilization, Vegan Branched Chain Protein Pre/Post Workout
  • MAXIMUM RESULTS👉 Includes BCAA - 99% bioavailability - ensure optimum nutrition and muscle recovery
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SaleBest Seller No. 17
Theacrine (Teacrine) - Energy and Stamina Boosting Supplement - 100 Mg - 60 Capsules
  • ENHANCE ENERGY - Theacrine provides a noticable boost to mental and physical energy similar to that of caffeine.
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  • MADE IN USA - This nootropic is manufactured right here in the USA, using high quality, pure, Theacrine
SaleBest Seller No. 18
Cissus Quadrangularis Super Extract, 150 Capsules, Made in The USA, Dietary Supplement for Joint and Tendon Pain, 1000mg Serving Size
  • REBUILD CARTILAGE - Cissus may help the body make Collagen which helps repair damaged fibers and connects cells/tissue to each other.
  • SUPPORTS JOINT HEALTH - Cissus Extract has been shown to help reduce joint pain and promote healthy joints
  • MADE IN THE USA - Our Cissus Extract is manufactured right here in the USA in New York city.
  • THIRD PARTY TESTED - Our Cissus Extract has been third party tested for Phytosterol content.
SaleBest Seller No. 19
Leaky Gut Defense - 168gm Powder (appox 30 servings per container) | Formulated For Optimal Healing - Stevia-FREE! Now Sweetened with Monk Fruit | Contains: L-Glutamine, Arabinogalactan, Licorice Root 10:1 (deglycyrrhized) | Aloe Leaf (standardized to 50% polysaccharides) | Pharmaceutical Grade
  • Leaky Gut Defense is Stevia-FREE, it's sweetened with Monk Fruit for added health benefits. Comes in a convenient powdered form, easy to mix. This formula is optimized for healing over taste. Manufactured in the USA in a GMP-certified facility, for guaranteed quality and potency.
  • GASTROINTESTINAL SUPPORT - Helps heal leaky gut and repair the digestive lining. Enhanced production of short chain fatty acids.*
  • CUSTOM FORMULA: Contains - 3 g of L-Glutamine, Licorice Root 10:1(deglycyrrhized), Aloe Leaf (standardized to 50% polysaccharides), Arabinogalactan, & Monk Fruit
  • BENEFITS - Support for: Dysbiosis (leaky gut syndrome), IBS, food allergies and/or sensitivities, malabsorption, stomach pain, digestive problems, weight issues, gas/bloating, bowel issues, and more.*
  • MONEY BACK GUARANTEE - 100% RISK FREE: If Leaky Gut Defense isn't the best supplement you've ever tried, simply return the bottle (even if empty) for 100% refund of your purchase price! ***ONLY APPLIES TO SMALL SIZED JAR (168gm/30 servings)***
Best Seller No. 20
Agrilabs Prohibit Soluble Drench Powder
  • Broad spectrum anthelmintic
  • Broad coverage of nine major types of worms
  • Short withdrawal time
  • Low volume dosage cattle 2 mL/100 lbs sheep 1 mL/50 lbs
  • Cost effective and well targeted

Top Reasons to Consider Sustamine

Sustamine® is a dipeptide consisting of two amino acids (L-alanine and L-glutamine) connected by a peptide bond. Sustamine is stable in both heat and acids, is highly soluble, and can function as a source of glutamine in the body.

Sustamine® is an ingredient that may assist with hydration and support exercise performance* Ultra-pure, clinically tested, Sustamine® is produced through a patented fermentation method to create a unique dipeptide that is more easily absorbed by the body than complex protein molecules.

Everyone has heard of glutamine, yet it’s supplement cousin, L-Alanyl-L-Glutamine, may be less familiar to many of you. Even its snappier name, Sustamine™ – is it just me, or does that sounds like a ’90s grunge band? – may not ring a bell. However, a growing body of science is causing quite a chorus of support for this unique dipeptide.

Alanylglutamine is a stable and soluble delivery form of glutamine, but are there benefits to consuming this dipeptide that go beyond what you’d expect from a glutamine and alanine supplement? I’m here to sort through the science and let you know.

What Is It?
Before diving into alanylglutamine, let’s do a brief review of its constituent parts, L-alanine and L-glutamine.

Only then will you understand why this dipeptide could help any serious athlete or physique trainer reach their goals.

Alanine is categorized as a non-essential amino acid, whereas glutamine is conditionally essential.

Yet both are vitally involved in the exchange of nitrogen between tissues and the production and/or storage of glucose.

Both affect hydration. Both are significantly affected by strenuous exercise and other forms of physiological stress.

They seem like a match made in supplement heaven.

The functions of alanine and glutamine don’t just occur in parallel; they’re incredibly synergistic:

Alanine is the most important amino acid involved in carrying nitrogen from muscle to the liver. Once there, the amino acid’s carbon skeleton can be converted to glucose as part of a process called the glucose-alanine cycle.
Glutamine is the primary transporter between cells of nitrogen derived from protein breakdown, and it stimulates glucose-like peptide-1 (GLP-1). So glutamine helps maintain blood glucose levels and supports glycogen synthesis.
Both amino acids also improve hydration in synergistic ways. Alanine appears to influence cellular hydration and volume by raising intracellular potassium concentrations, thereby drawing water into the cell. Glutamine helps maintain your body’s overall acid-base balance, because the ammonia that’s cleaved from the amino acid and delivered to the kidneys affects water transport.

In response to strenuous exercise or other forms of physiological stress, both amino acids are released from muscle in significant concentrations. If muscle concentrations of these amino acids aren’t restored, exercise performance and recovery – not to mention immune function, muscle growth and a host of other biological functions – can suffer.

Put it all together, and it’s not hard to see how any bodybuilder or athlete could benefit from taking alanine and glutamine together.

Which bring us back to L-Alanyl-L-Glutamine. Unlike a whole protein that contains peptide fractions of all sizes – with some having thousands of peptide bonds – alanylglutamine contains just one peptide bond, linking L-alanine and L-glutamine.

This single peptide fragment is called a dipeptide. (If there were a third amino acid added to this chemical, it’d be called a tripeptide. Protein fractions with more than three joined amino acids are referred to as oligopeptides.)

The benefit of consuming a dipeptide versus a mixture of its two free-form amino acids is largely a matter of stability, solubility and absorption efficiency. Specifically, whereas L-glutamine is rapidly degraded to ammonia when put into solution and is poorly soluble, alanylglutamine is incredibly soluble.

Some studies suggest that it may remain stable for more than five years! And whereas free amino acids compete for uptake via highly selective amino acid transporters, dipeptides are more efficiently absorbed via minimally selective transporters, called PEPT1 transporters.

Think of amino acid transporters as selective “bouncers” that who only let A-listers into their club, one at a time. PEPT1 transporters are “bouncers” who don’t care who enters, so long as they show up in pairs or in groups of three. Because of the easier access, blood amino acid concentrations can rise faster when di- and tri-peptides are consumed versus free amino acids.

What Does It Do?
In animal models, alanylglutamine infusion has been reported to increase nitrogen retention and weight gain; decrease muscle and whole-body protein breakdown and leucine oxidation; increase gut integrity, function and circulation; and provide support against tissue damage.

Unfortunately, few human studies have looked at alanylglutamine consumed orally rather than clinically. Drs. Roger Harris and Jay Hoffman did surmise that blood glutamine concentrations were almost 60 percent higher when subjects drank a beverage containing alanylglutamine rather than a free-form L-glutamine. Even more impressive, total plasma glutamine concentrations were almost 126% higher in response to alanylglutamine.

This and other data seems to indicate that alanine and glutamine concentrations in the blood rise significantly in response to oral alanylglutamine supplementation, and that the resulting L-glutamine is preferentially used to synthesize l-citrulline and l-arginine.

Interestingly enough, chronic ingestion of alanylglutamine appears to significantly increase muscle glutamine concentrations more than chronic L-glutamine supplementation; however, no difference in muscle glutamine stores has been reported in response to acute immediately post-exercise with either the free or dipeptide form of glutamine.

It has also been reported that chronic supplementation of either the dipeptide or equal doses of free L-alanine and L-glutamine post-exercise, resulted in no significant differences for plasma glutamine, inflammatory response, or antioxidative capacity.

Though not universal, much of the research suggests equivocal results between the use of the dipeptide versus its constituent free amino acids.

What are the performance and physique applications?
Adding alanylglutamine to a rehydration solution is significantly more effective at increasing water and electrolyte absorption than consuming either a glutamine- or glucose-containing solution.

In a study by Hoffman and associates, the researchers concluded that the increase in performance that they observed in college kids cycling to exhaustion was likely due to an increase in water and electrolyte absorption after taking a Sustamine-containing solution. Ingestion of a Sustamine-containing solution delayed the onset of fatigue under mild dehydration by almost 190%, compared to dehydrated conditions.

Hoffman’s team has also presented evidence that 1 g of alanylglutamine per 500 mL of water maintains athletic skill performance and visual reaction time better than water only Division I female athletes who became dehydrated and then drank a solution. Doubling the dose of the dipeptide per 500 mL of water decreased fatigue but did not improve performance or reaction time.

Though no human studies have looked at whether oral alanylglutamine promotes muscle hypertrophy or strength, it seems likely that such a beneficial effect would be observed under conditions of high training volumes, very low carb intake, poor hydration, or some combination of the three.

What’s the bottom line?
Though the research on oral alanylglutamine and its effects on performance and body composition remains in its infancy, the early data looks very promising.

Its role in sparing muscle protein, supporting endurance or high-intensity training performance and recovery, supporting exercise in the heat, promoting hydration and healthy immune system function, and possibly serving as a synergist during low-carb dieting all make alanylglutamine a powerful active ingredient to consider adding to your supplement toolbox.


Real Supplements gives you the best Sustamine on the market today. Our top-rated lists are fresh and current so you get the best options.

Amazon Best Seller Products List Last Updated on 2019-08-22